Granular cell tumor of the neurohypophysis: A single-institution experience

Manolo Piccirilli, Vincenza Maiola, Maurizio Salvati, Alessandro D'Elia, Alessandro Di Paolo, Domenico Campagna, Antonio Santoro, Roberto Delfini

Research output: Contribution to journalArticle


Granular cell tumor (GCT) is a rare neoplasm occurring in the sellar and suprasellar spaces. It is a primary tumor of the neurohypophysis, presumably arising from the pituicytes, a distinctive glial cell of the neurohypophysis. GCTs in most reported cases show biologically benign behavior with slow growth. Only 70 cases of hypophyseal GCTs have been reported in the literature. We report a case of GCT in the neurohypophysis of a 46-year-old woman and discuss the histological and clinical features of this neoplasm together with the treatment modalities, reviewing the pertinent literature.

Original languageEnglish
Pages (from-to)e160-e164
Issue number4
Publication statusPublished - Jul 1 2014


  • Granular cell tumor
  • Hypophysis
  • Pituicytoma
  • Surgery

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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    Piccirilli, M., Maiola, V., Salvati, M., D'Elia, A., Di Paolo, A., Campagna, D., Santoro, A., & Delfini, R. (2014). Granular cell tumor of the neurohypophysis: A single-institution experience. Tumori, 100(4), e160-e164.