Granular-cell tumours of the skin do not express carcino-embryonic antigen

J. Kanitakis, G. Zambruno, J. Viac, J. Thivolet

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Granular-cell tumour (GCT) of the skin is an uncommon tumour of disputed histogenesis, that has been subjected to several immunohistochemical studies. The controversy existing in the literature concerning the expression of carcinoembryonic antigen (CEA) by GCT prompted us to study a series of 17 cases of cutaneous GCT by using an avidin-biotin-immunoperoxidase technique on routinely-processed tissue sections. No CEA activity was detected in any of the tumours screened. The reasons for this controversy are discussed.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalJournal of Cutaneous Pathology
Issue number5
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine


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