Granulomatous slack skin: Cytogenetic and molecular analyses

Paola Grammatico, Laurian Balus, Susanna Scarpa, Liliana Varesco, Cristiana Di Rosa, Barbara Grammatico, Giuseppe Del Porto

Research output: Contribution to journalArticlepeer-review


Granulomatous slack skin (GSS) is a rare disorder which is considered a slowly evolving T-cell lymphoma associated with granulomatous inflammation that mediates clastolysis. A combined cytogenetic, molecular, and cellular analysis was conducted on a clinically and histologically defined case of GSS. Cell cultures obtained from the skin biopsy showed trisomy of chromosome 8, and the DNA sample extracted from the skin biopsy showed a T-cell receptor β-chain rearrangement.

Original languageEnglish
Pages (from-to)96-100
Number of pages5
JournalCancer Genetics and Cytogenetics
Issue number2
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology


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