Gross pathologic types of hepatocellular carcinoma in Italy

Tommaso Stroffolini, Pietro Andreone, Angelo Andriulli, Antonio Ascione, Antonio Craxi, Maria Chiaramonte, Domenico Galante, Onofrio Giuseppe Manghisi, Roberto Mazzanti, Cinzia Medaglia, Giampaolo Pilleri, Gian Ludovico Rapaccini, Maddalena Albanese, Gloria Taliani, Maria Elena Tosti, Erica Villa, Giovanni Gasbarrini

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The prevalence and independent predictors of the different macroscopic types of hepatocellular carcinoma (HCC) were assessed in 1,073 unselected patients of 14 hospitals in Italy from May 1996 to May 1997. Solitary HCC was the most common cancer type (44.6%), followed by multinodular (44.2%), diffuse (8.4%) and massive (2.8%) types. After adjustment for the influence of confounders by multiple logistic regression analysis, Child-Pugh grades B and C were found to be independent predictors of multinodular (odds ratio, OR, 2.0; 95% confidence interval (CI) = 1.5-2.6) and diffuse (OR 2.6; 95% CI = 1.6-4.4) HCC types. These findings indicate that the majority of HCC cases are not detected at a potentially treatable stage. Delayed detection of HCC is associated with a higher likelihood of the multinodular or diffuse gross pathologic type.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalOncology
Volume56
Issue number3
Publication statusPublished - Apr 1999

Fingerprint

Italy
Hepatocellular Carcinoma
Confidence Intervals
Logistic Models
Odds Ratio
Regression Analysis
Neoplasms

Keywords

  • Gross pathology
  • Hepatocellular carcinoma
  • Italy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Stroffolini, T., Andreone, P., Andriulli, A., Ascione, A., Craxi, A., Chiaramonte, M., ... Gasbarrini, G. (1999). Gross pathologic types of hepatocellular carcinoma in Italy. Oncology, 56(3), 189-192.

Gross pathologic types of hepatocellular carcinoma in Italy. / Stroffolini, Tommaso; Andreone, Pietro; Andriulli, Angelo; Ascione, Antonio; Craxi, Antonio; Chiaramonte, Maria; Galante, Domenico; Manghisi, Onofrio Giuseppe; Mazzanti, Roberto; Medaglia, Cinzia; Pilleri, Giampaolo; Rapaccini, Gian Ludovico; Albanese, Maddalena; Taliani, Gloria; Tosti, Maria Elena; Villa, Erica; Gasbarrini, Giovanni.

In: Oncology, Vol. 56, No. 3, 04.1999, p. 189-192.

Research output: Contribution to journalArticle

Stroffolini, T, Andreone, P, Andriulli, A, Ascione, A, Craxi, A, Chiaramonte, M, Galante, D, Manghisi, OG, Mazzanti, R, Medaglia, C, Pilleri, G, Rapaccini, GL, Albanese, M, Taliani, G, Tosti, ME, Villa, E & Gasbarrini, G 1999, 'Gross pathologic types of hepatocellular carcinoma in Italy', Oncology, vol. 56, no. 3, pp. 189-192.
Stroffolini T, Andreone P, Andriulli A, Ascione A, Craxi A, Chiaramonte M et al. Gross pathologic types of hepatocellular carcinoma in Italy. Oncology. 1999 Apr;56(3):189-192.
Stroffolini, Tommaso ; Andreone, Pietro ; Andriulli, Angelo ; Ascione, Antonio ; Craxi, Antonio ; Chiaramonte, Maria ; Galante, Domenico ; Manghisi, Onofrio Giuseppe ; Mazzanti, Roberto ; Medaglia, Cinzia ; Pilleri, Giampaolo ; Rapaccini, Gian Ludovico ; Albanese, Maddalena ; Taliani, Gloria ; Tosti, Maria Elena ; Villa, Erica ; Gasbarrini, Giovanni. / Gross pathologic types of hepatocellular carcinoma in Italy. In: Oncology. 1999 ; Vol. 56, No. 3. pp. 189-192.
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