Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines

D. Matteucci, M. Paglianti, A. M. Giangregorio, M. R. Capobianchi, F. Dianzani, M. Bendinelli

Research output: Contribution to journalArticle

Abstract

Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.

Original languageEnglish
Pages (from-to)651-654
Number of pages4
JournalJournal of Virology
Volume56
Issue number2
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Immunology

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    Matteucci, D., Paglianti, M., Giangregorio, A. M., Capobianchi, M. R., Dianzani, F., & Bendinelli, M. (1985). Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines. Journal of Virology, 56(2), 651-654.