Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.
|Number of pages||4|
|Journal||Journal of Virology|
|Publication status||Published - 1985|
ASJC Scopus subject areas