Group B Streptococcus prevalence in pregnancy and maternal-fetal transmission: A multicenter study

N. Natale, P. A. Bertuletti, A. Goglio, G. Pasinetti, F. Della Fiorentina, M. Parea, L. Falasca, D. Consilvio, R. Meo, R. Cavadini, G. Amuso, M. Cappato, M. R. Pelucchi, A. Raglio, S. A. Garsia, A. Giollo, C. Soldavini, C. Sturla, M. De Rosa

Research output: Contribution to journalArticlepeer-review


Objective: To evaluate the prevalence of Streptococcus agalactiae (GBS) in pregnancy and the rate of transmission to the newborns. Material and Methods: 7176 consecutive mother-newborn pairs from single pregnancies were analyzed in 23 Italian hospitals. Vaginal and/or rectal swabs in labor and, in some cases, during pregnancy and swabs from infants at birth were collected in a 3-month period. Results: At delivery, vaginal (9.8%) was slightly greater than rectal (7.9%) colonization. Vaginal carrier status ranged from 3.7% to 22% in the various centers. No relation was found between GBS prevalence and sample size or geographical localization. The prevalence was similar to that in recent italian literature, the figures being lower than those reported in other countries. Conclusions: In pregnancy (36 weeks of gestation) the prevalence of GBS was greater (12.1%) than at delivery (10.7%) and rectal (11.1%) was more frequent than vaginal (9.8%) colonization. Vertical transmission of GBS to newborns occurred in 43.2% of culture-positive untreated women. Three newborns developed early onset sepsis; their mothers were all colonized and remained untreated.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalItalian Journal of Gynaecology and Obstetrics
Issue number3
Publication statusPublished - 1995


  • Delivery
  • Neonatal sepsis
  • Newborn
  • Pregnancy
  • Streptococcus agalactiae

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


Dive into the research topics of 'Group B Streptococcus prevalence in pregnancy and maternal-fetal transmission: A multicenter study'. Together they form a unique fingerprint.

Cite this