Fattori di crescita nella terapia delle ulcere cutanee croniche degli arti inferiori

Translated title of the contribution: Growth factors in the treatmnet of chronic skin ulcers of the lower limbs

M. T. Viviano, F. Cianfarani, T. Odorisio, L. M. Chinni, M. Papi

Research output: Contribution to journalArticle


We report our experience in 8 patients affected with chronic cutaneous ulcerations of the lower limbs who have been treated with local periulcerative injections of granulocyte-macrophage colony stimulating factor (GM-CSF, Mielogen fl 150 μg, Schering-Plough). The clinical beneficial effect obtained stimulated us to investigate the mechanism of action of GM-CSF on wound healing. Thus, we report the preliminary results of the "in situ" hybridazion analysis expression on local expression of vascular epidermal growth factor after treatment with GM-CSF.

Original languageItalian
Pages (from-to)43-46
Number of pages4
JournalImpegno Ospedaliero, Sezione Scientifica
Issue number1-2
Publication statusPublished - 2002


ASJC Scopus subject areas

  • Medicine(all)

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