Growth hormone (GH) treatment in GH-deficient adults: Effects on muscle size, strength and neural activation

A. Sartorio; M. V. Narici

Growth hormone (GH) treatment in GH-deficient adults: Effects on muscle size, strength and neural activation

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of 6 months of recombinant growth hormone (GH) treatment (0.5 IU kg^-1 per week) on muscle size, strength and neural activation (EMG) was studied in eight adults with childhood onset GH deficiency (GHD). Before treatment, height, body mass (BM) and lean body mass (LBM) of the GHD subjects were significantly lower (P2 was found between the two groups. By contrast, LLV(M+B)/height³ was 82.0±19.0% that of the controls (P3 of the GHD patients after treatment was no longer significantly different from that of the controls. Quadriceps MVC increased by 9.8±12.0% (P

Original language	English
Pages (from-to)	527-537
Number of pages	11
Journal	Clinical Physiology
Volume	14
Issue number	5
Publication status	Published - 1994

Keywords

GH deficiency
Growth hormone
Hypopituitarism
Muscle cross-sectional area
Muscle strength

ASJC Scopus subject areas

Physiology

Cite this

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abstract = "The effects of 6 months of recombinant growth hormone (GH) treatment (0.5 IU kg-1 per week) on muscle size, strength and neural activation (EMG) was studied in eight adults with childhood onset GH deficiency (GHD). Before treatment, height, body mass (BM) and lean body mass (LBM) of the GHD subjects were significantly lower (P2 was found between the two groups. By contrast, LLV(M+B)/height3 was 82.0±19.0% that of the controls (P3 of the GHD patients after treatment was no longer significantly different from that of the controls. Quadriceps MVC increased by 9.8±12.0% (P",

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AB - The effects of 6 months of recombinant growth hormone (GH) treatment (0.5 IU kg-1 per week) on muscle size, strength and neural activation (EMG) was studied in eight adults with childhood onset GH deficiency (GHD). Before treatment, height, body mass (BM) and lean body mass (LBM) of the GHD subjects were significantly lower (P2 was found between the two groups. By contrast, LLV(M+B)/height3 was 82.0±19.0% that of the controls (P3 of the GHD patients after treatment was no longer significantly different from that of the controls. Quadriceps MVC increased by 9.8±12.0% (P

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KW - Hypopituitarism

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Growth hormone (GH) treatment in GH-deficient adults: Effects on muscle size, strength and neural activation

Abstract

Keywords

ASJC Scopus subject areas

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