Growth hormone (GH) treatment in GH-deficient adults: Effects on muscle size, strength and neural activation

A. Sartorio, M. V. Narici

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of 6 months of recombinant growth hormone (GH) treatment (0.5 IU kg-1 per week) on muscle size, strength and neural activation (EMG) was studied in eight adults with childhood onset GH deficiency (GHD). Before treatment, height, body mass (BM) and lean body mass (LBM) of the GHD subjects were significantly lower (P2 was found between the two groups. By contrast, LLV(M+B)/height3 was 82.0±19.0% that of the controls (P3 of the GHD patients after treatment was no longer significantly different from that of the controls. Quadriceps MVC increased by 9.8±12.0% (P

Original languageEnglish
Pages (from-to)527-537
Number of pages11
JournalClinical Physiology
Volume14
Issue number5
Publication statusPublished - 1994

Keywords

  • GH deficiency
  • Growth hormone
  • Hypopituitarism
  • Muscle cross-sectional area
  • Muscle strength

ASJC Scopus subject areas

  • Physiology

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