Abstract
The effects of 6 months of recombinant growth hormone (GH) treatment (0.5 IU kg-1 per week) on muscle size, strength and neural activation (EMG) was studied in eight adults with childhood onset GH deficiency (GHD). Before treatment, height, body mass (BM) and lean body mass (LBM) of the GHD subjects were significantly lower (P2 was found between the two groups. By contrast, LLV(M+B)/height3 was 82.0±19.0% that of the controls (P3 of the GHD patients after treatment was no longer significantly different from that of the controls. Quadriceps MVC increased by 9.8±12.0% (P
| Original language | English |
|---|---|
| Pages (from-to) | 527-537 |
| Number of pages | 11 |
| Journal | Clinical Physiology |
| Volume | 14 |
| Issue number | 5 |
| Publication status | Published - 1994 |
Keywords
- GH deficiency
- Growth hormone
- Hypopituitarism
- Muscle cross-sectional area
- Muscle strength
ASJC Scopus subject areas
- Physiology