Growth hormone secretion in pubertal and adult subjects

F. Minuto, A. Barreca, S. Ferrini, G. Mazzocchi, P. Del Monte, G. Giordano

Research output: Contribution to journalArticlepeer-review


GH responsiveness to insulin-induced hypoglycaemia and its circadian secretion were studied in a group of subjects in different pubertal stages. The GH peak after insulin was minimal in stage 1 boys (7.6 ± 1.3 (SEM) ng/ml) and increased progressively, in parallel with pubertal maturation, reaching a maximum in the adult state (20 ± 4.0 ng/ml); the basal value was superimposable in all groups studied. The circadian secretion showed a sleep-related surge which was almost identical in the different stages; however in pubertal stage 1 boys multiple secretory peaks were observed, mainly during waking hours. A statistically significant difference (P

Original languageEnglish
Pages (from-to)161-165
Number of pages5
JournalActa Endocrinologica
Issue number2
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Endocrinology

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