Growth inhibitory and differentiating effects of sodium butyrate on human neuroblastoma cells in culture

P. Rocchi, A. M. Ferreri, G. Simone, D. Granchi, P. Paolucci, G. Paolucci

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of sodium butyrate (NaB) on cell growth and expression of morphological and biochemical properties was examined in the human neuroblastoma cell lines AF8 and SJ-N-KP. The obtained data show that NaB induced a marked growth inhibition and morphological differentiation while it was ineffective in inducing biochemical differentiation.

Original languageEnglish
Pages (from-to)917-920
Number of pages4
JournalAnticancer Research
Volume12
Issue number3
Publication statusPublished - 1992

Keywords

  • Differentiation
  • Neuroblastoma
  • Sodium butyrate

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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