Guidelines for radiation therapy of lung cancer in the elderly

A. Gava, V. Zagonel, L. Repetto, C. Gravetto, F. Ferrarese, C. Gridelli

Research output: Contribution to journalArticlepeer-review

Abstract

Lung cancer is the main cause of death from cancer. As for other malignant tumors, the age-associated incidence rate increases with age reaching a peak towards 70 years. No guidelines are available for the elderly. Surgery remains the election therapy for non small cell lung cancer apart from the presence of major contraindications. In inoperable cases for the general condition or patient refusal, radiotherapy represents an effective alternative. In advanced stages radiotherapy alone finds its indication even if outcomes are disappointing. The introduction in the clinical practice of active well-tolerated drugs as vinorelbine and gemcitabine affords new therapeutic perspectives. In small cell lung cancer, for the early systemic dissemination also at the initial stages, improvements with exclusive radiotherapy are of short duration. Combined radiation and chemotherapy improves local control at the thoracic level.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalRays - International Journal of Radiological Sciences
Volume24
Issue number2 SUPPL.
Publication statusPublished - 1999

Keywords

  • Elderly
  • Lung cancer
  • Radiotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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