Abstract
Background: Guidewire (GW) cannulation can reduce the risk of post-ERCP pancreatitis (PEP) by avoiding the opacification of the main pancreatic duct. Objective: To compare the effects of conventional contrast ERCP and GW cannulation of the common bile duct on the rate of PEP in low- and high-risk patients. Design: Prospective, comparative-intervention single-center study. Setting: Tertiary referral center. Patients: Patients with biliary disease with an intact papilla were prospectively examined by ERCP. Interventions: Biliary cannulation using a sphincterotome with contrast injection (ConI) or a hydrophilic GW without contrast injection. Main Outcome Measurements: Pancreatitis rate in the GW group and the contrast injection (ConI) group. Results: PEP occurred in 60 of 1249 patients (4.8%), 35 of 678 (5.2%) in the GW group and 25 of 571 (4.4%) in the ConI group (not significant). The overall rate of PEP was significantly higher in high-risk patients (12.2%) than in low-risk patients (3.5%) (P
| Original language | English |
|---|---|
| Pages (from-to) | 339-346 |
| Number of pages | 8 |
| Journal | Gastrointestinal Endoscopy |
| Volume | 75 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2012 |
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Keywords
- acute recurrent pancreatitis
- ARP
- CBD
- CI
- common bile duct
- confidence interval
- ConI
- contrast injection
- guidewire
- GW
- main pancreatic duct
- MPD
- PEP
- post-ERCP pancreatitis
- SOD
- sphincter of Oddi dysfunction
ASJC Scopus subject areas
- Gastroenterology
- Radiology Nuclear Medicine and imaging
Cite this
Guidewire biliary cannulation does not reduce post-ERCP pancreatitis compared with the contrast injection technique in low-risk and high-risk patients. / Mariani, Alberto; Giussani, Antonella; Di Leo, Milena; Testoni, Sabrina; Testoni, Pier Alberto.
In: Gastrointestinal Endoscopy, Vol. 75, No. 2, 02.2012, p. 339-346.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Guidewire biliary cannulation does not reduce post-ERCP pancreatitis compared with the contrast injection technique in low-risk and high-risk patients
AU - Mariani, Alberto
AU - Giussani, Antonella
AU - Di Leo, Milena
AU - Testoni, Sabrina
AU - Testoni, Pier Alberto
PY - 2012/2
Y1 - 2012/2
N2 - Background: Guidewire (GW) cannulation can reduce the risk of post-ERCP pancreatitis (PEP) by avoiding the opacification of the main pancreatic duct. Objective: To compare the effects of conventional contrast ERCP and GW cannulation of the common bile duct on the rate of PEP in low- and high-risk patients. Design: Prospective, comparative-intervention single-center study. Setting: Tertiary referral center. Patients: Patients with biliary disease with an intact papilla were prospectively examined by ERCP. Interventions: Biliary cannulation using a sphincterotome with contrast injection (ConI) or a hydrophilic GW without contrast injection. Main Outcome Measurements: Pancreatitis rate in the GW group and the contrast injection (ConI) group. Results: PEP occurred in 60 of 1249 patients (4.8%), 35 of 678 (5.2%) in the GW group and 25 of 571 (4.4%) in the ConI group (not significant). The overall rate of PEP was significantly higher in high-risk patients (12.2%) than in low-risk patients (3.5%) (P
AB - Background: Guidewire (GW) cannulation can reduce the risk of post-ERCP pancreatitis (PEP) by avoiding the opacification of the main pancreatic duct. Objective: To compare the effects of conventional contrast ERCP and GW cannulation of the common bile duct on the rate of PEP in low- and high-risk patients. Design: Prospective, comparative-intervention single-center study. Setting: Tertiary referral center. Patients: Patients with biliary disease with an intact papilla were prospectively examined by ERCP. Interventions: Biliary cannulation using a sphincterotome with contrast injection (ConI) or a hydrophilic GW without contrast injection. Main Outcome Measurements: Pancreatitis rate in the GW group and the contrast injection (ConI) group. Results: PEP occurred in 60 of 1249 patients (4.8%), 35 of 678 (5.2%) in the GW group and 25 of 571 (4.4%) in the ConI group (not significant). The overall rate of PEP was significantly higher in high-risk patients (12.2%) than in low-risk patients (3.5%) (P
KW - acute recurrent pancreatitis
KW - ARP
KW - CBD
KW - CI
KW - common bile duct
KW - confidence interval
KW - ConI
KW - contrast injection
KW - guidewire
KW - GW
KW - main pancreatic duct
KW - MPD
KW - PEP
KW - post-ERCP pancreatitis
KW - SOD
KW - sphincter of Oddi dysfunction
UR - http://www.scopus.com/inward/record.url?scp=84855858688&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84855858688&partnerID=8YFLogxK
U2 - 10.1016/j.gie.2011.09.002
DO - 10.1016/j.gie.2011.09.002
M3 - Article
C2 - 22075192
AN - SCOPUS:84855858688
VL - 75
SP - 339
EP - 346
JO - Gastrointestinal Endoscopy
JF - Gastrointestinal Endoscopy
SN - 0016-5107
IS - 2
ER -