TY - JOUR
T1 - Gynecologic cancer intergroup (GCIG) consensus review for squamous cell carcinoma of the ovary
AU - Glasspool, Rosalind M.
AU - Martín, Antonio González
AU - Millan, David
AU - Lorusso, Domenica
AU - Avall-Lundqvist, Elisabeth
AU - Hurteau, Jean A
AU - Davis, Alison
AU - Hilpert, Felix
AU - Kim, Jae Weon
AU - Alexandre, Jérôme
AU - Ledermann, Jonathan A.
PY - 2014/11/1
Y1 - 2014/11/1
N2 - Squamous cell carcinoma of the ovary is a rare complication of mature cystic teratoma. The epidemiology, pathology, diagnosis, and management of this rare tumor are reviewed. Clinical characteristics, preoperative imaging, and tumor markers may help to predict malignancy preoperatively. Complete cytoreduction should be the aim of surgery. The prognosis for stage 1A disease is good, but for women with advanced or recurrent disease, it is very poor and has not improved in recent years. At present, there are insufficient data to provide clear guidance on the optimal management strategy for advanced disease, and there is a need to gain an understanding of the biology and to develop novel effective therapies. This will require coordinated international collaboration.
AB - Squamous cell carcinoma of the ovary is a rare complication of mature cystic teratoma. The epidemiology, pathology, diagnosis, and management of this rare tumor are reviewed. Clinical characteristics, preoperative imaging, and tumor markers may help to predict malignancy preoperatively. Complete cytoreduction should be the aim of surgery. The prognosis for stage 1A disease is good, but for women with advanced or recurrent disease, it is very poor and has not improved in recent years. At present, there are insufficient data to provide clear guidance on the optimal management strategy for advanced disease, and there is a need to gain an understanding of the biology and to develop novel effective therapies. This will require coordinated international collaboration.
KW - GCIG
KW - Mature cystic teratoma
KW - Mature teratoma
KW - Review
KW - Squamous cell carcinoma of ovary
UR - http://www.scopus.com/inward/record.url?scp=84988692362&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84988692362&partnerID=8YFLogxK
U2 - 10.1097/IGC.0000000000000209
DO - 10.1097/IGC.0000000000000209
M3 - Review article
C2 - 25126954
AN - SCOPUS:84988692362
VL - 24
SP - S26-S29
JO - International Journal of Gynecological Cancer
JF - International Journal of Gynecological Cancer
SN - 1048-891X
IS - 9
ER -