TY - JOUR
T1 - Habituation to pain in "medication overuse headache"
T2 - A CO 2 laser-evoked potential study
AU - Ferraro, Diana
AU - Vollono, Catello
AU - Miliucci, Roberto
AU - Virdis, Daniela
AU - De Armas, Liala
AU - Pazzaglia, Costanza
AU - Le Pera, Domenica
AU - Tarantino, Samuela
AU - Balestri, Martina
AU - Di Trapani, Girolamo
AU - Valeriani, Massimiliano
PY - 2012/5
Y1 - 2012/5
N2 - Objective.- Our aim was to investigate CO2 laser-evoked potential (LEP) habituation to experimental pain in a group of patients affected by medication-overuse headache, with a history of episodic migraine becoming chronic, before and after treatment, consisting in acute medication withdrawal and a preventive treatment cycle. Background.- One of the main features of LEPs in migraineurs is a lower habituation to repetitive noxious stimuli during the interictal phase. Methods.- LEPs were recorded to stimulation of both the right hand and the right perioral region in 14 patients and in 14 healthy subjects. The habituation of both the N1 and the vertex N2/P2 components was assessed by measuring the LEP amplitude changes across 3 consecutive repetitions of 30 trials each. Results.- In the 8 patients who had clinically improved after treatment, the N2/P2 amplitude habituation was significantly higher after treatment than before treatment following both hand (F = 43.2, P
AB - Objective.- Our aim was to investigate CO2 laser-evoked potential (LEP) habituation to experimental pain in a group of patients affected by medication-overuse headache, with a history of episodic migraine becoming chronic, before and after treatment, consisting in acute medication withdrawal and a preventive treatment cycle. Background.- One of the main features of LEPs in migraineurs is a lower habituation to repetitive noxious stimuli during the interictal phase. Methods.- LEPs were recorded to stimulation of both the right hand and the right perioral region in 14 patients and in 14 healthy subjects. The habituation of both the N1 and the vertex N2/P2 components was assessed by measuring the LEP amplitude changes across 3 consecutive repetitions of 30 trials each. Results.- In the 8 patients who had clinically improved after treatment, the N2/P2 amplitude habituation was significantly higher after treatment than before treatment following both hand (F = 43.2, P
KW - habituation
KW - laser-evoked potential
KW - medication-overuse headache
KW - migraine
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U2 - 10.1111/j.1526-4610.2012.02151.x
DO - 10.1111/j.1526-4610.2012.02151.x
M3 - Article
C2 - 22512411
AN - SCOPUS:84860739587
VL - 52
SP - 792
EP - 807
JO - Headache
JF - Headache
SN - 0017-8748
IS - 5
ER -