Haemodynamic and volumetric monitoring during haemorrhagic shock in swine

Lucia Martini, Milena Fini, Gianluca Giavaresi, Stefano Faenza, Flavia Petrini, Roberto Giardino

Research output: Contribution to journalArticle

Abstract

Various studies have been performed concerning haemodynamics in the shock state. The aim of this study was to examine if a haemodynamic approach based on volumetric indices can offer a new method of evaluation. Volumetric measurements of ventricular filling and cardiac function were compared with classical haemodynamic variables during induced haemorrhagic shock in swine. Twelve hybrid swine were anaesthetized and underwent arteriectomy to induce haemorrhagic shock. Blood was collected in ACD treated bags and reinfused via the same vein after a shock period of 90 min. Haemodynamic and volume measurements were evaluated. Seven swine survived to complete the protocol and reached the final experimental time (90 min after reinfusion), while the remaining five died 1 h after reinfusion. Concerning the haemodynamics, afterload changes characterized the haemorrhagic shock period, while blood volume distribution dictated ventricular filling and ventricular kinetics during the post-reinfusion period. Systemic vascular resistance was different in the two groups. This study suggests that blood volumetric evaluations can offer better comparative data than pulmonary catheterisation for a precise assessment of cardiac output. Preload values have turned out to be of greater relevance than traditional pressure variables.

Original languageEnglish
Pages (from-to)69-76
Number of pages8
JournalResuscitation
Volume51
Issue number1
DOIs
Publication statusPublished - 2001

Fingerprint

Hemorrhagic Shock
Swine
Hemodynamics
Shock
Blood Volume
Catheterization
Cardiac Output
Vascular Resistance
Veins
Pressure
Lung

Keywords

  • Blood pressure
  • Cardiac output
  • Haemodynamics
  • Oximetry
  • Shock

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing(all)

Cite this

Haemodynamic and volumetric monitoring during haemorrhagic shock in swine. / Martini, Lucia; Fini, Milena; Giavaresi, Gianluca; Faenza, Stefano; Petrini, Flavia; Giardino, Roberto.

In: Resuscitation, Vol. 51, No. 1, 2001, p. 69-76.

Research output: Contribution to journalArticle

Martini, Lucia ; Fini, Milena ; Giavaresi, Gianluca ; Faenza, Stefano ; Petrini, Flavia ; Giardino, Roberto. / Haemodynamic and volumetric monitoring during haemorrhagic shock in swine. In: Resuscitation. 2001 ; Vol. 51, No. 1. pp. 69-76.
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