Six lambs, where extracorporeal blood flow ranging between 600 and 1000 ml min-1 was continuously maintained, were mechanically ventilated in two different modes: continuous positive pressure ventilation (CPPV) with 5 cm H2O PEEP and low frequency positive pressure ventilation with 5 cm H2O PEEP and extracorporeal CO2 removal through a carbon dioxide membrane lung (LEPPV-ECCO2R). The blood gases were in normal ranges through both CPPV and LFPPV-ECCO2R, even if a higher PaO2 was found during CPPV. However, during LFPPV-ECCO2R, cardiac output increased about 30%, O2 transport 19.3%, while heart rate, pulmonary artery pressure and arterial pressure did not change. LFPPV-ECCO2R, in the experiments, seems to overcome some hemodynamic impairments of CPPV.
|Translated title of the contribution||Haemodynamic responses during low frequency positive pressure ventilation with extracorporeal CO2 removal (LFPPV-ECCO2R). A comparison with positive pressure ventilation (CPPV)|
|Number of pages||13|
|Journal||Anasthesiologie und Intensivmedizin|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine