Haemolytic uraemic syndrome: Therapeutic effect of plasma infusion

R. Misiani, A. C. Appiani, A. Edefonti, E. Gotti, A. Bettinelli, M. Giani, E. Rossi, G. Remuzzi, G. Mecca

Research output: Contribution to journalArticlepeer-review

Abstract

The therapeutic effect of plasma infusion was evaluated in 10 children and seven adults with haemolytic uraemic syndrome. All but one patient responded to this treatment with rapid disappearace of haematological abnormalities. The patient who apparently failed to respond to plasma infusion obtained complete remission of the disease after plasmapheresis. Although 15 of the 17 patients were anuric or oliguric on admission, renal function recovered completely in eight children and two adults. Seven patients showed residual chronic renal failure and two required long-term maintenance haemodialysis. Treatment with plasma was also successful in patients with relapses or recurrent episodes. Plasma infusion is a promising therapeutic approach for the haemolytic uraemic syndrome and deserves further study in clinical trials.

Original languageEnglish
Pages (from-to)1304-1306
Number of pages3
JournalBritish Medical Journal
Volume285
Issue number6351
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Medicine(all)

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