Haemophilia: strategies for carrier detection and prenatal diagnosis.

I. R. Peake, D. P. Lillicrap, V. Boulyjenkov, E. Briet, V. Chan, E. K. Ginter, E. M. Kraus, R. Ljung, P. M. Mannucci, K. Nicolaides

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

In 1977 WHO published in the Bulletin a Memorandum on Methods for the Detection of Haemophilia Carriers. This was produced following a WHO/WFH (World Federation of Haemophilia) Meeting of Investigators in Geneva in November 1976, and has served as a valuable reference article on the genetics of haemophilia. The analyses discussed were based on phenotypic assessment, which, at that time, was the only procedure available. The molecular biology revolution in genetics during the 1980s made enormous contributions to our understanding of the molecular basis of the haemophilias and now permits precise carrier detection and prenatal diagnosis. WHO and WFH held a joint meeting on this subject in February 1992 in Geneva. This article is the result of these discussions.

Original languageEnglish
Pages (from-to)429-458
Number of pages30
JournalBulletin of the World Health Organization
Volume71
Issue number3-4
Publication statusPublished - 1993

Fingerprint

Hemophilia A
Prenatal Diagnosis
Molecular Biology
Research Personnel

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Peake, I. R., Lillicrap, D. P., Boulyjenkov, V., Briet, E., Chan, V., Ginter, E. K., ... Nicolaides, K. (1993). Haemophilia: strategies for carrier detection and prenatal diagnosis. Bulletin of the World Health Organization, 71(3-4), 429-458.

Haemophilia : strategies for carrier detection and prenatal diagnosis. / Peake, I. R.; Lillicrap, D. P.; Boulyjenkov, V.; Briet, E.; Chan, V.; Ginter, E. K.; Kraus, E. M.; Ljung, R.; Mannucci, P. M.; Nicolaides, K.

In: Bulletin of the World Health Organization, Vol. 71, No. 3-4, 1993, p. 429-458.

Research output: Contribution to journalArticle

Peake, IR, Lillicrap, DP, Boulyjenkov, V, Briet, E, Chan, V, Ginter, EK, Kraus, EM, Ljung, R, Mannucci, PM & Nicolaides, K 1993, 'Haemophilia: strategies for carrier detection and prenatal diagnosis.', Bulletin of the World Health Organization, vol. 71, no. 3-4, pp. 429-458.
Peake IR, Lillicrap DP, Boulyjenkov V, Briet E, Chan V, Ginter EK et al. Haemophilia: strategies for carrier detection and prenatal diagnosis. Bulletin of the World Health Organization. 1993;71(3-4):429-458.
Peake, I. R. ; Lillicrap, D. P. ; Boulyjenkov, V. ; Briet, E. ; Chan, V. ; Ginter, E. K. ; Kraus, E. M. ; Ljung, R. ; Mannucci, P. M. ; Nicolaides, K. / Haemophilia : strategies for carrier detection and prenatal diagnosis. In: Bulletin of the World Health Organization. 1993 ; Vol. 71, No. 3-4. pp. 429-458.
@article{117c36ee30ab4440b20c60e361c412d9,
title = "Haemophilia: strategies for carrier detection and prenatal diagnosis.",
abstract = "In 1977 WHO published in the Bulletin a Memorandum on Methods for the Detection of Haemophilia Carriers. This was produced following a WHO/WFH (World Federation of Haemophilia) Meeting of Investigators in Geneva in November 1976, and has served as a valuable reference article on the genetics of haemophilia. The analyses discussed were based on phenotypic assessment, which, at that time, was the only procedure available. The molecular biology revolution in genetics during the 1980s made enormous contributions to our understanding of the molecular basis of the haemophilias and now permits precise carrier detection and prenatal diagnosis. WHO and WFH held a joint meeting on this subject in February 1992 in Geneva. This article is the result of these discussions.",
author = "Peake, {I. R.} and Lillicrap, {D. P.} and V. Boulyjenkov and E. Briet and V. Chan and Ginter, {E. K.} and Kraus, {E. M.} and R. Ljung and Mannucci, {P. M.} and K. Nicolaides",
year = "1993",
language = "English",
volume = "71",
pages = "429--458",
journal = "Bulletin of the World Health Organization",
issn = "0043-9686",
publisher = "World Health Organization",
number = "3-4",

}

TY - JOUR

T1 - Haemophilia

T2 - strategies for carrier detection and prenatal diagnosis.

AU - Peake, I. R.

AU - Lillicrap, D. P.

AU - Boulyjenkov, V.

AU - Briet, E.

AU - Chan, V.

AU - Ginter, E. K.

AU - Kraus, E. M.

AU - Ljung, R.

AU - Mannucci, P. M.

AU - Nicolaides, K.

PY - 1993

Y1 - 1993

N2 - In 1977 WHO published in the Bulletin a Memorandum on Methods for the Detection of Haemophilia Carriers. This was produced following a WHO/WFH (World Federation of Haemophilia) Meeting of Investigators in Geneva in November 1976, and has served as a valuable reference article on the genetics of haemophilia. The analyses discussed were based on phenotypic assessment, which, at that time, was the only procedure available. The molecular biology revolution in genetics during the 1980s made enormous contributions to our understanding of the molecular basis of the haemophilias and now permits precise carrier detection and prenatal diagnosis. WHO and WFH held a joint meeting on this subject in February 1992 in Geneva. This article is the result of these discussions.

AB - In 1977 WHO published in the Bulletin a Memorandum on Methods for the Detection of Haemophilia Carriers. This was produced following a WHO/WFH (World Federation of Haemophilia) Meeting of Investigators in Geneva in November 1976, and has served as a valuable reference article on the genetics of haemophilia. The analyses discussed were based on phenotypic assessment, which, at that time, was the only procedure available. The molecular biology revolution in genetics during the 1980s made enormous contributions to our understanding of the molecular basis of the haemophilias and now permits precise carrier detection and prenatal diagnosis. WHO and WFH held a joint meeting on this subject in February 1992 in Geneva. This article is the result of these discussions.

UR - http://www.scopus.com/inward/record.url?scp=0027351077&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027351077&partnerID=8YFLogxK

M3 - Article

C2 - 8324863

AN - SCOPUS:0027351077

VL - 71

SP - 429

EP - 458

JO - Bulletin of the World Health Organization

JF - Bulletin of the World Health Organization

SN - 0043-9686

IS - 3-4

ER -