Abstract
With the aim of investigating a possible relationship between 'objective' halitosis (established by sulfide levels in the breath) and Helicobacter pylori, we performed a study in 58 dyspeptic patients reported to suffer from 'bad breath.' Furthermore, we evaluated the effects on halitosis of eradication therapy (only for H. pylori-positive patients) and chlorhexidine antiseptic mouth rinses (in all patients). Sulfide compound assay indicated objective halitosis in 52/58 patients, 30 of whom were positive and 22 negative for H. pylori. In 19/30 eradication by double therapy provoked a decrease to below the cutoff value of sulfide levels in 15. In the other 11 of the 30 subjects, in whom H. pylori positivity persisted, halitosis parameters did not change. Chlorexidine reduced sulfides to below the cutoff value in 16/22 H. pylori-negative patients, but did not provoke any change in the 11 unsuccessfully treated H. pylori-positive subjects. In these, objective halitosis disappeared only after a successful eradication by triple therapy (9/11). Our results show a possible association between halitosis and H. pylori since bacterial eradication may resolve the symptom. Antiseptic mouthwashes may be effective only in absence of H. pylori, when halitosis may be due to oral putrefactive microbial activity. In a small number of subjects the cause and treatment of halitosis need to be clarified.
| Original language | English |
|---|---|
| Pages (from-to) | 2733-2737 |
| Number of pages | 5 |
| Journal | Digestive Diseases and Sciences |
| Volume | 43 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 1998 |
Fingerprint
Keywords
- Bad breath
- Dyspepsia
- Halitosis
- Helicobacter pylori
ASJC Scopus subject areas
- Gastroenterology
Cite this
Halitosis and Helicobacter pylori : A possible relationship. / Ierardi, Enzo; Amoruso, Annacinzia; La Notte, Teresa; Francavilla, Ruggiero; Castellaneta, Stefania; Marrazza, Elisa; Monno, Rosa Anna; Francavilla, Antonio.
In: Digestive Diseases and Sciences, Vol. 43, No. 12, 1998, p. 2733-2737.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Halitosis and Helicobacter pylori
T2 - A possible relationship
AU - Ierardi, Enzo
AU - Amoruso, Annacinzia
AU - La Notte, Teresa
AU - Francavilla, Ruggiero
AU - Castellaneta, Stefania
AU - Marrazza, Elisa
AU - Monno, Rosa Anna
AU - Francavilla, Antonio
PY - 1998
Y1 - 1998
N2 - With the aim of investigating a possible relationship between 'objective' halitosis (established by sulfide levels in the breath) and Helicobacter pylori, we performed a study in 58 dyspeptic patients reported to suffer from 'bad breath.' Furthermore, we evaluated the effects on halitosis of eradication therapy (only for H. pylori-positive patients) and chlorhexidine antiseptic mouth rinses (in all patients). Sulfide compound assay indicated objective halitosis in 52/58 patients, 30 of whom were positive and 22 negative for H. pylori. In 19/30 eradication by double therapy provoked a decrease to below the cutoff value of sulfide levels in 15. In the other 11 of the 30 subjects, in whom H. pylori positivity persisted, halitosis parameters did not change. Chlorexidine reduced sulfides to below the cutoff value in 16/22 H. pylori-negative patients, but did not provoke any change in the 11 unsuccessfully treated H. pylori-positive subjects. In these, objective halitosis disappeared only after a successful eradication by triple therapy (9/11). Our results show a possible association between halitosis and H. pylori since bacterial eradication may resolve the symptom. Antiseptic mouthwashes may be effective only in absence of H. pylori, when halitosis may be due to oral putrefactive microbial activity. In a small number of subjects the cause and treatment of halitosis need to be clarified.
AB - With the aim of investigating a possible relationship between 'objective' halitosis (established by sulfide levels in the breath) and Helicobacter pylori, we performed a study in 58 dyspeptic patients reported to suffer from 'bad breath.' Furthermore, we evaluated the effects on halitosis of eradication therapy (only for H. pylori-positive patients) and chlorhexidine antiseptic mouth rinses (in all patients). Sulfide compound assay indicated objective halitosis in 52/58 patients, 30 of whom were positive and 22 negative for H. pylori. In 19/30 eradication by double therapy provoked a decrease to below the cutoff value of sulfide levels in 15. In the other 11 of the 30 subjects, in whom H. pylori positivity persisted, halitosis parameters did not change. Chlorexidine reduced sulfides to below the cutoff value in 16/22 H. pylori-negative patients, but did not provoke any change in the 11 unsuccessfully treated H. pylori-positive subjects. In these, objective halitosis disappeared only after a successful eradication by triple therapy (9/11). Our results show a possible association between halitosis and H. pylori since bacterial eradication may resolve the symptom. Antiseptic mouthwashes may be effective only in absence of H. pylori, when halitosis may be due to oral putrefactive microbial activity. In a small number of subjects the cause and treatment of halitosis need to be clarified.
KW - Bad breath
KW - Dyspepsia
KW - Halitosis
KW - Helicobacter pylori
UR - http://www.scopus.com/inward/record.url?scp=0032440473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032440473&partnerID=8YFLogxK
U2 - 10.1023/A:1026619831442
DO - 10.1023/A:1026619831442
M3 - Article
C2 - 9881507
AN - SCOPUS:0032440473
VL - 43
SP - 2733
EP - 2737
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
SN - 0163-2116
IS - 12
ER -