Halting the progression of chronic nephropathy

Ruth C. Campbell, Piero Ruggenenti, Giuseppe Remuzzi

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The incidence of end-stage renal disease (ESRD) is increasing worldwide. In the United States alone, there were 372,000 patients requiring renal replacement therapy in the year 2000 and is expected to rise to 650,000 by the year 2010. The trends in Europe and Japan are forecasted to follow a similar path. These increases represent a significant burden to countries worldwide; not only due to the financial costs of providing ESRD care, but also because of lost productivity and significant morbidity and mortality for the affected patients. There is clearly a pressing need for the aggressive identification and early treatment of patients with nephropathy to prevent progression to ESRD. Research in the last 25 yr has made great advances in the understanding of the progression of chronic renal disease in diabetic and nondiabetic proteinuric nephropathy. There are now effective treatment options that can slow the progression of chronic nephropathies in many individuals, and ongoing research has raised the tantalizing prospect of the reversal of renal disease progression.

Original languageEnglish
JournalJournal of the American Society of Nephrology
Volume13
Issue numberSUPPL. 3
Publication statusPublished - Nov 1 2002

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Chronic Kidney Failure
Renal Replacement Therapy
Chronic Renal Insufficiency
Research
Disease Progression
Japan
Morbidity
Kidney
Costs and Cost Analysis
Mortality
Incidence
Therapeutics

ASJC Scopus subject areas

  • Nephrology

Cite this

Halting the progression of chronic nephropathy. / Campbell, Ruth C.; Ruggenenti, Piero; Remuzzi, Giuseppe.

In: Journal of the American Society of Nephrology, Vol. 13, No. SUPPL. 3, 01.11.2002.

Research output: Contribution to journalArticle

Campbell, Ruth C. ; Ruggenenti, Piero ; Remuzzi, Giuseppe. / Halting the progression of chronic nephropathy. In: Journal of the American Society of Nephrology. 2002 ; Vol. 13, No. SUPPL. 3.
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