Abstract
Background. Haptic robots allow the exploitation of known motor learning mechanisms, representing a valuable option for motor treatment after stroke. The aim of this feasibility multicentre study was to test the clinical efficacy of a haptic prototype, for the recovery of hand function after stroke. Methods. A prospective pilot clinical trial was planned on 15 consecutive patients enrolled in 3 rehabilitation centre in Italy. All the framework features of the haptic robot (e.g., control loop, external communication, and graphic rendering for virtual reality) were implemented into a real-time MATLAB/Simulink environment, controlling a five-bar linkage able to provide forces up to 20 [N] at the end effector, used for finger and hand rehabilitation therapies. Clinical (i.e., Fugl-Meyer upper extremity scale; nine hold pegboard test) and kinematics (i.e., time; velocity; jerk metric; normalized jerk of standard movements) outcomes were assessed before and after treatment to detect changes in patients' motor performance. Reorganization of cortical activation was detected in one patient by fMRI. Results and Conclusions. All patients showed significant improvements in both clinical and kinematic outcomes. Additionally, fMRI results suggest that the proposed approach may promote a better cortical activation in the brain.
| Original language | English |
|---|---|
| Article number | 895492 |
| Journal | Computational and Mathematical Methods in Medicine |
| Volume | 2013 |
| DOIs | |
| Publication status | Published - 2013 |
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ASJC Scopus subject areas
- Applied Mathematics
- Modelling and Simulation
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
- Immunology and Microbiology(all)
Cite this
Haptic-based neurorehabilitation in poststroke patients : A feasibility prospective multicentre trial for robotics hand rehabilitation. / Turolla, Andrea; Daud Albasini, Omar A.; Oboe, Roberto; Agostini, Michela; Tonin, Paolo; Paolucci, Stefano; Sandrini, Giorgio; Venneri, Annalena; Piron, Lamberto.
In: Computational and Mathematical Methods in Medicine, Vol. 2013, 895492, 2013.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Haptic-based neurorehabilitation in poststroke patients
T2 - A feasibility prospective multicentre trial for robotics hand rehabilitation
AU - Turolla, Andrea
AU - Daud Albasini, Omar A.
AU - Oboe, Roberto
AU - Agostini, Michela
AU - Tonin, Paolo
AU - Paolucci, Stefano
AU - Sandrini, Giorgio
AU - Venneri, Annalena
AU - Piron, Lamberto
PY - 2013
Y1 - 2013
N2 - Background. Haptic robots allow the exploitation of known motor learning mechanisms, representing a valuable option for motor treatment after stroke. The aim of this feasibility multicentre study was to test the clinical efficacy of a haptic prototype, for the recovery of hand function after stroke. Methods. A prospective pilot clinical trial was planned on 15 consecutive patients enrolled in 3 rehabilitation centre in Italy. All the framework features of the haptic robot (e.g., control loop, external communication, and graphic rendering for virtual reality) were implemented into a real-time MATLAB/Simulink environment, controlling a five-bar linkage able to provide forces up to 20 [N] at the end effector, used for finger and hand rehabilitation therapies. Clinical (i.e., Fugl-Meyer upper extremity scale; nine hold pegboard test) and kinematics (i.e., time; velocity; jerk metric; normalized jerk of standard movements) outcomes were assessed before and after treatment to detect changes in patients' motor performance. Reorganization of cortical activation was detected in one patient by fMRI. Results and Conclusions. All patients showed significant improvements in both clinical and kinematic outcomes. Additionally, fMRI results suggest that the proposed approach may promote a better cortical activation in the brain.
AB - Background. Haptic robots allow the exploitation of known motor learning mechanisms, representing a valuable option for motor treatment after stroke. The aim of this feasibility multicentre study was to test the clinical efficacy of a haptic prototype, for the recovery of hand function after stroke. Methods. A prospective pilot clinical trial was planned on 15 consecutive patients enrolled in 3 rehabilitation centre in Italy. All the framework features of the haptic robot (e.g., control loop, external communication, and graphic rendering for virtual reality) were implemented into a real-time MATLAB/Simulink environment, controlling a five-bar linkage able to provide forces up to 20 [N] at the end effector, used for finger and hand rehabilitation therapies. Clinical (i.e., Fugl-Meyer upper extremity scale; nine hold pegboard test) and kinematics (i.e., time; velocity; jerk metric; normalized jerk of standard movements) outcomes were assessed before and after treatment to detect changes in patients' motor performance. Reorganization of cortical activation was detected in one patient by fMRI. Results and Conclusions. All patients showed significant improvements in both clinical and kinematic outcomes. Additionally, fMRI results suggest that the proposed approach may promote a better cortical activation in the brain.
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UR - http://www.scopus.com/inward/citedby.url?scp=84890073766&partnerID=8YFLogxK
U2 - 10.1155/2013/895492
DO - 10.1155/2013/895492
M3 - Article
C2 - 24319496
AN - SCOPUS:84890073766
VL - 2013
JO - Computational and Mathematical Methods in Medicine
JF - Computational and Mathematical Methods in Medicine
SN - 1748-670X
M1 - 895492
ER -