Hashimoto's encephalopathy in the elderly: Relationship to cognitive impairment

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Hashimoto's encephalopathy (HE) is a steroid-responsive encephalopathy associated with high titers of antithyroid antibodies. To date, 57 pediatric-, adult-, and elderly-onset cases have been described in the literature. The clinical picture is pleomorphic, and cognitive impairment is a frequently reported symptom. We report the case of a patient with slowly progressive cognitive impairment possibly caused by HE. The issue of the differential diagnosis with primary dementia is discussed. A review of cases of HE showing cognitive deterioration is also presented, and factors possibly related to characteristics of cognitive impairment and outcome after therapy are considered.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalJournal of Geriatric Psychiatry and Neurology
Issue number3
Publication statusPublished - Sep 2002

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Geriatrics and Gerontology
  • Neuroscience(all)


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