Polyclonal and monoclonal radioimmunoassay for HBsAg were performed in 58 subjects with acute or chronic NANB hepatitis (group A), in 7 with chronic non-B hepatitis (group B), in 7 with acute hepatitis due to HAV, CMV, or EBV (group C), in 2 subjects non-responders to HBV vaccine (group D), and in 20 subjects with acute or chronic HBV infection (group E). In group A, all patients were HBs negative by both methods, but 3 DA who were found positive only by M-RIA. Patients of group B, C, and D were HBs negative by both techniques. In group E HBs was evidenced in 5 patients by M-RIA whereas the research by polyclonal RIA was negative. The research of HBs by M-RIA is a useful technique being more sensitive than the polyclonal assay.
|Number of pages||6|
|Journal||Annali dell'Istituto Superiore di Sanita|
|Publication status||Published - 1988|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health