Hbv and hdv: New treatments on the horizon

Valentina Zuccaro, Erika Asperges, Marta Colaneri, Lea Nadia Marvulli, Raffaele Bruno

Research output: Contribution to journalReview articlepeer-review


Despite the accumulating knowledge, chronic hepatitis B (CHB) and HDV infection rep-resent a global health problem, and there are still several critical issues, which frequently remain uncovered. In this paper, we provided an overview of the current therapeutic options and summa-rized the investigational therapies in the pipeline. Furthermore, we discussed some critical issues such as a “functional cure” approach, the futility of long-term NA therapy and the relevance of understanding drug actions and safety of antivirals, especially in special populations.

Original languageEnglish
Article number4054
JournalJournal of Clinical Medicine
Issue number18
Publication statusPublished - Sep 2021


  • Antivirals
  • Functional cure
  • HBV
  • HDV
  • Pharmacology

ASJC Scopus subject areas

  • Medicine(all)


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