HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy

Maria Cristina Medici; Annalisa Aloisi; Monica Martinelli; Laura Anna Abelli; Francesca Casula; Pierpaolo Valcavi; Giuseppe Dettori; Carlo Chezzi

HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy

Maria Cristina Medici, Annalisa Aloisi, Monica Martinelli, Laura Anna Abelli, Francesca Casula, Pierpaolo Valcavi, Giuseppe Dettori, Carlo Chezzi

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.

Original language	English
Pages (from-to)	63-67
Number of pages	5
Journal	New Microbiologica
Volume	29
Issue number	1
Publication status	Published - Jan 2006

Keywords

Antiviral-resistant variants
Genotype
HBV

ASJC Scopus subject areas

Microbiology (medical)
Microbiology

Fingerprint Dive into the research topics of 'HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy'. Together they form a unique fingerprint.

Cite this

HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy. / Medici, Maria Cristina; Aloisi, Annalisa; Martinelli, Monica; Abelli, Laura Anna; Casula, Francesca; Valcavi, Pierpaolo; Dettori, Giuseppe; Chezzi, Carlo.

In: New Microbiologica, Vol. 29, No. 1, 01.2006, p. 63-67.

Research output: Contribution to journal › Article › peer-review

@article{65aa12dc34cb4ccb99149cf52ca0bf2a,

title = "HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy",

abstract = "HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.",

keywords = "Antiviral-resistant variants, Genotype, HBV",

author = "Medici, {Maria Cristina} and Annalisa Aloisi and Monica Martinelli and Abelli, {Laura Anna} and Francesca Casula and Pierpaolo Valcavi and Giuseppe Dettori and Carlo Chezzi",

year = "2006",

month = jan,

language = "English",

volume = "29",

pages = "63--67",

journal = "New Microbiologica",

issn = "1121-7138",

publisher = "Luigi Ponzio e figlio Editori",

number = "1",

}

TY - JOUR

T1 - HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy

AU - Medici, Maria Cristina

AU - Aloisi, Annalisa

AU - Martinelli, Monica

AU - Abelli, Laura Anna

AU - Casula, Francesca

AU - Valcavi, Pierpaolo

AU - Dettori, Giuseppe

AU - Chezzi, Carlo

PY - 2006/1

Y1 - 2006/1

N2 - HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.

AB - HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.

KW - Antiviral-resistant variants

KW - Genotype

KW - HBV

UR - http://www.scopus.com/inward/record.url?scp=33645558302&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645558302&partnerID=8YFLogxK

M3 - Article

C2 - 16608127

AN - SCOPUS:33645558302

VL - 29

SP - 63

EP - 67

JO - New Microbiologica

JF - New Microbiologica

SN - 1121-7138

IS - 1

ER -