HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy

Maria Cristina Medici, Annalisa Aloisi, Monica Martinelli, Laura Anna Abelli, Francesca Casula, Pierpaolo Valcavi, Giuseppe Dettori, Carlo Chezzi

Research output: Contribution to journalArticlepeer-review

Abstract

HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.

Original languageEnglish
Pages (from-to)63-67
Number of pages5
JournalNew Microbiologica
Volume29
Issue number1
Publication statusPublished - Jan 2006

Keywords

  • Antiviral-resistant variants
  • Genotype
  • HBV

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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