HBV, HDV and HIV infections in 242 drug addicts: Two-year follow-up

C. Mandelli, M. Cesana, P. Ferroni, G. P. Lorini, G. P. Aimo, A. Tagger, P. A. Bianchi, D. Conte

Research output: Contribution to journalArticle

Abstract

Of 242 north Italian heroin addicts, 24 (9.9%) were HBsAg positive. HBeAg was positive in two of them (8.3%), anti-HBe in 16 (66.6%) and anti-HDV in 21 (87.5%). Of the 218 HBsAg negative, 182 (83.5%) had anti-HBc, 72 (33.0%) anti-HBe and 97 (44.5%) anti-HBs. One-hundred-eighty-five drug addicts were anti-HIV positive (76.4%); 77 of these (41.6%) were asymptomatic, 93 (50.3%) had PGL and 15 (8.1%) ARC. T4+ cell count was significantly lower in subjects with ARC as was T4+/T8+ ratio in subjects with PGL and ARC. During a median follow-up of 9.5 months (range 4-25), we observed three new cases of hepatitis (two caused by NANBV and one by HBV with HDV coinfection) and one new HIV infection. Ten anti-HIV positive subjects developed PGL and one AIDS.

Original languageEnglish
Pages (from-to)318-321
Number of pages4
JournalEuropean Journal of Epidemiology
Volume4
Issue number3
DOIs
Publication statusPublished - Sep 1988

Keywords

  • Drug addicts
  • Hepatitis B
  • Hepatitis delta
  • Human immunodeficiency virus

ASJC Scopus subject areas

  • Epidemiology

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    Mandelli, C., Cesana, M., Ferroni, P., Lorini, G. P., Aimo, G. P., Tagger, A., Bianchi, P. A., & Conte, D. (1988). HBV, HDV and HIV infections in 242 drug addicts: Two-year follow-up. European Journal of Epidemiology, 4(3), 318-321. https://doi.org/10.1007/BF00148917