HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

Nicola Coppola; Giovanna Loquercio; Gilda Tonziello; Rosa Azzaro; Mariantonietta Pisaturo; Gaetano Di Costanzo; Mario Starace; Giuseppe Pasquale; Carmela Cacciapuoti; Arnolfo Petruzziello

doi:10.1016/j.jcv.2013.06.020

HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

Nicola Coppola, Giovanna Loquercio, Gilda Tonziello, Rosa Azzaro, Mariantonietta Pisaturo, Gaetano Di Costanzo, Mario Starace, Giuseppe Pasquale, Carmela Cacciapuoti, Arnolfo Petruzziello

Istituto Nazionale Tumori Fondazione G. Pascale

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg.

Original language	English
Pages (from-to)	315-317
Number of pages	3
Journal	Journal of Clinical Virology
Volume	58
Issue number	1
DOIs	https://doi.org/10.1016/j.jcv.2013.06.020
Publication status	Published - Sep 2013

Keywords

HBsAg mutants
HBV infection
Occult HBV infection
Transfusion

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.1016/j.jcv.2013.06.020

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Coppola, N., Loquercio, G., Tonziello, G., Azzaro, R., Pisaturo, M., Di Costanzo, G., Starace, M., Pasquale, G., Cacciapuoti, C., & Petruzziello, A. (2013). HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient. Journal of Clinical Virology, 58(1), 315-317. https://doi.org/10.1016/j.jcv.2013.06.020

HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient. / Coppola, Nicola; Loquercio, Giovanna; Tonziello, Gilda; Azzaro, Rosa; Pisaturo, Mariantonietta; Di Costanzo, Gaetano; Starace, Mario; Pasquale, Giuseppe; Cacciapuoti, Carmela; Petruzziello, Arnolfo.

In: Journal of Clinical Virology, Vol. 58, No. 1, 09.2013, p. 315-317.

Research output: Contribution to journal › Article › peer-review

Coppola, N, Loquercio, G, Tonziello, G, Azzaro, R, Pisaturo, M, Di Costanzo, G, Starace, M, Pasquale, G, Cacciapuoti, C & Petruzziello, A 2013, 'HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient', Journal of Clinical Virology, vol. 58, no. 1, pp. 315-317. https://doi.org/10.1016/j.jcv.2013.06.020

Coppola, Nicola ; Loquercio, Giovanna ; Tonziello, Gilda ; Azzaro, Rosa ; Pisaturo, Mariantonietta ; Di Costanzo, Gaetano ; Starace, Mario ; Pasquale, Giuseppe ; Cacciapuoti, Carmela ; Petruzziello, Arnolfo. / HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient. In: Journal of Clinical Virology. 2013 ; Vol. 58, No. 1. pp. 315-317.

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abstract = "We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg.",

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AU - Azzaro, Rosa

AU - Pisaturo, Mariantonietta

AU - Di Costanzo, Gaetano

AU - Starace, Mario

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HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

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Keywords

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