HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

Nicola Coppola, Giovanna Loquercio, Gilda Tonziello, Rosa Azzaro, Mariantonietta Pisaturo, Gaetano Di Costanzo, Mario Starace, Giuseppe Pasquale, Carmela Cacciapuoti, Arnolfo Petruzziello

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg.

Original languageEnglish
Pages (from-to)315-317
Number of pages3
JournalJournal of Clinical Virology
Volume58
Issue number1
DOIs
Publication statusPublished - Sep 2013

Keywords

  • HBsAg mutants
  • HBV infection
  • Occult HBV infection
  • Transfusion

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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