HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients.

E. Savoldi, F. Gargiulo, M. G. Marinone, F. Favilli, F. Callea, P. L. Sapelli, A. Turano

Research output: Contribution to journalArticle

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Abstract

BACKGROUND: HCV-RNA occurrence in saliva of patients suffering from C hepatitis induced to consider saliva as a possible diffusion mean of this disease. METHODS: Saliva and blood samples from 32 C hepatitis seropositive patients, followed for odontostomatologic problems in Odontoiatric Clinic of Brescia University were obtained. In every blood and saliva sample HCV-RNA concentration was evaluated following HCV-RNA 2.0 Assay (bDNA) Quantiplex test (Chiron), in Microbiology Institute of Brescia University. RESULTS: All patients showing HCV-RNA in serum presented virus in saliva also; two patients with negative HCV-RNA serum presented virus in saliva. In latter cases, we supposed that viral concentration in serum was under sensibility threshold of employed method. CONCLUSIONS: Saliva appears an easily and not invasively obtainable medium for epidemiological studies on HCV diffusion in humans. Its role in C hepatitis transmission, on the contrary, has not been cleared till now.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalMinerva Stomatologica
Volume50
Issue number3-4
Publication statusPublished - 2001

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Saliva
RNA
Hepatitis C
Branched DNA Signal Amplification Assay
Serum
Viruses
Microbiology
Epidemiologic Studies

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Savoldi, E., Gargiulo, F., Marinone, M. G., Favilli, F., Callea, F., Sapelli, P. L., & Turano, A. (2001). HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients. Minerva Stomatologica, 50(3-4), 71-74.

HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients. / Savoldi, E.; Gargiulo, F.; Marinone, M. G.; Favilli, F.; Callea, F.; Sapelli, P. L.; Turano, A.

In: Minerva Stomatologica, Vol. 50, No. 3-4, 2001, p. 71-74.

Research output: Contribution to journalArticle

Savoldi, E, Gargiulo, F, Marinone, MG, Favilli, F, Callea, F, Sapelli, PL & Turano, A 2001, 'HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients.', Minerva Stomatologica, vol. 50, no. 3-4, pp. 71-74.
Savoldi E, Gargiulo F, Marinone MG, Favilli F, Callea F, Sapelli PL et al. HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients. Minerva Stomatologica. 2001;50(3-4):71-74.
Savoldi, E. ; Gargiulo, F. ; Marinone, M. G. ; Favilli, F. ; Callea, F. ; Sapelli, P. L. ; Turano, A. / HCV-RNA occurrence in saliva of odontoiatric HCV seropositive patients. In: Minerva Stomatologica. 2001 ; Vol. 50, No. 3-4. pp. 71-74.
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AU - Callea, F.

AU - Sapelli, P. L.

AU - Turano, A.

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