Abstract
To evaluate whether age over 70 years represents a prognostic factor in head and neck cancer, we reviewed all cases observed between 1981 and 1984. Four hundred and thirty-eight (438) patients were considered in relation to three age groups (≤ 59, 60-69, and ≥ 70 years, defined as non-elderly, mid-elderly and elderly respectively). The main parameters analyzed included histological diagnosis (no difference emerged among the three age groups); anatomical site (hypopharyngeal carcinoma was most frequent in non-elderly patients); TNM stage (an higher incidence of early stages was seen in the elderly); performance status (better in the non-elderly); previous illnesses (life-style related diseases were more frequent in the non-elderly); contraindications to surgery (more frequent in the elderly); surgical treatment ('en bloc' resections were more often employed in the non-elderly); post-operative complications and local control (no difference between the three groups); multiple primary malignancies (head and neck, oesophagus and lung were more frequent in non-elderly patients) and survival (no difference). Although age affects several features of head and neck cancer patients, it does not appear from the present study to be an independent prognostic factor for local control and survival. With regard to survival, stage appeared to be the most important prognostic factor.
| Original language | English |
|---|---|
| Pages (from-to) | 634-640 |
| Number of pages | 7 |
| Journal | Journal of Laryngology and Otology |
| Volume | 104 |
| Issue number | 8 |
| Publication status | Published - 1990 |
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ASJC Scopus subject areas
- Otorhinolaryngology
Cite this
Head and neck cancer and ageing : A retrospective study in 438 patients. / Barzan, L.; Veronesi, A.; Caruso, G.; Serraino, D.; Magri, D.; Zagonel, V.; Tirelli, U.; Comoretto, R.; Monfardini, S.
In: Journal of Laryngology and Otology, Vol. 104, No. 8, 1990, p. 634-640.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Head and neck cancer and ageing
T2 - A retrospective study in 438 patients
AU - Barzan, L.
AU - Veronesi, A.
AU - Caruso, G.
AU - Serraino, D.
AU - Magri, D.
AU - Zagonel, V.
AU - Tirelli, U.
AU - Comoretto, R.
AU - Monfardini, S.
PY - 1990
Y1 - 1990
N2 - To evaluate whether age over 70 years represents a prognostic factor in head and neck cancer, we reviewed all cases observed between 1981 and 1984. Four hundred and thirty-eight (438) patients were considered in relation to three age groups (≤ 59, 60-69, and ≥ 70 years, defined as non-elderly, mid-elderly and elderly respectively). The main parameters analyzed included histological diagnosis (no difference emerged among the three age groups); anatomical site (hypopharyngeal carcinoma was most frequent in non-elderly patients); TNM stage (an higher incidence of early stages was seen in the elderly); performance status (better in the non-elderly); previous illnesses (life-style related diseases were more frequent in the non-elderly); contraindications to surgery (more frequent in the elderly); surgical treatment ('en bloc' resections were more often employed in the non-elderly); post-operative complications and local control (no difference between the three groups); multiple primary malignancies (head and neck, oesophagus and lung were more frequent in non-elderly patients) and survival (no difference). Although age affects several features of head and neck cancer patients, it does not appear from the present study to be an independent prognostic factor for local control and survival. With regard to survival, stage appeared to be the most important prognostic factor.
AB - To evaluate whether age over 70 years represents a prognostic factor in head and neck cancer, we reviewed all cases observed between 1981 and 1984. Four hundred and thirty-eight (438) patients were considered in relation to three age groups (≤ 59, 60-69, and ≥ 70 years, defined as non-elderly, mid-elderly and elderly respectively). The main parameters analyzed included histological diagnosis (no difference emerged among the three age groups); anatomical site (hypopharyngeal carcinoma was most frequent in non-elderly patients); TNM stage (an higher incidence of early stages was seen in the elderly); performance status (better in the non-elderly); previous illnesses (life-style related diseases were more frequent in the non-elderly); contraindications to surgery (more frequent in the elderly); surgical treatment ('en bloc' resections were more often employed in the non-elderly); post-operative complications and local control (no difference between the three groups); multiple primary malignancies (head and neck, oesophagus and lung were more frequent in non-elderly patients) and survival (no difference). Although age affects several features of head and neck cancer patients, it does not appear from the present study to be an independent prognostic factor for local control and survival. With regard to survival, stage appeared to be the most important prognostic factor.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025026402&partnerID=8YFLogxK
M3 - Article
VL - 104
SP - 634
EP - 640
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
SN - 0022-2151
IS - 8
ER -