Head and neck rhabdomyosarcomas in children: Value of clinical and CT findings in the detection of loco-regional relapses

R. Gilles, D. Couanet, R. Sigal, T. De Baere, A. Tardivon, J. Masselot, D. Vanel

Research output: Contribution to journalArticle

Abstract

Between 1984 and 1990, 16 children who had been treated for a histologically proven head and neck rhabdomyosarcoma developed 19 local recurrences. Fourteen relapses discovered in 11 children (group 1) were based on clinical data acquired 3 to 52 months after completion of treatment. Clinical symptoms (12 patients) or examination (2 patients) led to suspicion of a relapse. The clinical presentation of relapses and that of primary tumour were identical in eight cases. CT scans performed prior to recurrence revealed a stable 'post-therapeutic residue' without mass effect at the original site (12 patients) or was normal (2 patients). Six of these 11 children died at 1 to 15 months and five are alive 12 to 36 months after treatment of recurrence. Five relapses were discovered on CT studies 3 to 15 months after completion of treatment in the remaining five children (group 2). Clinical examination was normal in all cases. CT scans performed 3 months before recurrence showed a stable 'post-therapeutic residue' (4 patients) or was normal (1 patient). All of these five children died 3 to 23 months after the relapse.

Original languageEnglish
Pages (from-to)412-415
Number of pages4
JournalClinical Radiology
Volume49
Issue number6
DOIs
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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