Headache, seizures and repeated strokes in a young subject

A new case of MELAS-like syndrome?

G. Fabrizi, L. Manneschi, G. Marcacci, N. Volpi, P. Sabatelli, G. C. Guazzi, A. Federico

Research output: Contribution to journalArticle

Abstract

We report the case of a 21-year-old man affected by fluctuating stroke-like symptoms and computed-tomographic hypodensities, associated with seizures, headache, vomiting and a biochemically abnormal response of blood lactate and pyruvate after an oral glucose load. Muscle biopsy showed an increased number of subsarcolemmal mitochondria of increased size. Mitochondrial enzyme analysis was normal. The diagnosis of a MELAS-like mitochondrial disease even with minor muscle involvement is discussed.

Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalBrain Dysfunction
Volume1
Issue number3
Publication statusPublished - 1988

Fingerprint

MELAS Syndrome
Headache
Seizures
Stroke
Mitochondrial Size
Mitochondrial Diseases
Muscles
Pyruvic Acid
Vomiting
Lactic Acid
Biopsy
Glucose
Enzymes

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Fabrizi, G., Manneschi, L., Marcacci, G., Volpi, N., Sabatelli, P., Guazzi, G. C., & Federico, A. (1988). Headache, seizures and repeated strokes in a young subject: A new case of MELAS-like syndrome? Brain Dysfunction, 1(3), 161-168.

Headache, seizures and repeated strokes in a young subject : A new case of MELAS-like syndrome? / Fabrizi, G.; Manneschi, L.; Marcacci, G.; Volpi, N.; Sabatelli, P.; Guazzi, G. C.; Federico, A.

In: Brain Dysfunction, Vol. 1, No. 3, 1988, p. 161-168.

Research output: Contribution to journalArticle

Fabrizi, G, Manneschi, L, Marcacci, G, Volpi, N, Sabatelli, P, Guazzi, GC & Federico, A 1988, 'Headache, seizures and repeated strokes in a young subject: A new case of MELAS-like syndrome?', Brain Dysfunction, vol. 1, no. 3, pp. 161-168.
Fabrizi G, Manneschi L, Marcacci G, Volpi N, Sabatelli P, Guazzi GC et al. Headache, seizures and repeated strokes in a young subject: A new case of MELAS-like syndrome? Brain Dysfunction. 1988;1(3):161-168.
Fabrizi, G. ; Manneschi, L. ; Marcacci, G. ; Volpi, N. ; Sabatelli, P. ; Guazzi, G. C. ; Federico, A. / Headache, seizures and repeated strokes in a young subject : A new case of MELAS-like syndrome?. In: Brain Dysfunction. 1988 ; Vol. 1, No. 3. pp. 161-168.
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