Health care-associated infections in patients with head and neck cancer treated with chemotherapy and/or radiotherapy

Aurora Mirabile, Chiara Vismara, Fulvio Crippa, Paolo Bossi, Laura Locati, Cristiana Bergamini, Roberta Granata, Carlo Resteghini, Eutilia Conte, Daniele Morelli, Paolo Scarpellini, Lisa Licitra

Research output: Contribution to journalArticlepeer-review

Abstract

Background The incidence of health care-associated infections in patients with head and neck cancer receiving chemotherapy and/or radiotherapy (RT) is unknown. This retrospective study investigated the most common pathogens and their antibiotic sensitivity/resistance patterns in patients with head and neck cancer. Methods Infection rates in patients with head and neck cancer were analyzed over 2 periods (January 2005 to December 2009 and January 2010 to November 2012). Results In the first period, 140 health care-associated infections were observed among 2288 admissions, mostly because of gram-negative pathogens affecting the respiratory tract. In the second period, 212 health care-associated infections were observed. An increase in antibiotic resistance was reported. Health care-associated infections were more frequent with: male sex, age

Original languageEnglish
Pages (from-to)E1009-E1013
JournalHead and Neck
Volume38
DOIs
Publication statusPublished - Apr 1 2016

Keywords

  • chemotherapy
  • head and neck cancer
  • healthcare-acquired infections
  • nosocomial
  • radiotherapy

ASJC Scopus subject areas

  • Otorhinolaryngology

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