Health impact associated with vertebral deformities

Results from the european vertebral osteoporosis study (EVOS)

C. Matthis, U. Weber, T. W. O'Neill, H. Raspe, D. Agnusdei, K. Bergmann, C. Cooper, J. Dequeker, D. Felsenberg, J. A. Kanis, G. Kruskemper, H. Raspe, A. J. Silman, D. Felsenberg, E. H. Wieland, L. Kalidis, T. Lauermann, K. Weber, P. Geusens, I. Jajic & 53 others S. Havelka, P. Vavrincova, P. D. Delmas, F. Marchand, D. Banzer, S. Kirschner, W. Reisinger, J. Janot, H. Schatz, J. Franke, C. Scheidt-Nave, R. Ziegler, K. Abendroth, B. Felsch, A. Antoniou, G. Lyritis, C. Kiss, G. Poor, S. Ortolani, D. Agnusdei, C. Gennari, A. Hofman, H. A P Pols, J. A. Falch, H. E. Meyer, S. Czekalski, T. Miazgowski, K. Hoszowski, R. S. Lorenc, A. Aroso, A. Lopez, L. I. Benevolenskaya, E. E. Mikhailov, A. Letkovska, P. Masaryk, D. Roig Escofet, M. Ruiz Martin, M. Sosa, M. Diaz Curiel, A. Rapado, J. B. Cannata Andia, J. B. Diaz Lopez, O. Johnell, B. Nilsson, G. Dilsen, D. M. Reid, A. K. Bhalla, F. Ring, C. Todd, R. Williams, J. Reeve, R. Eastell, A. D. Woolf

Research output: Contribution to journalArticle

110 Citations (Scopus)

Abstract

To study the association between vertebral deformities and subjective health outcome indicators, including back pain and disability, a cross-sectional survey with spinal radiographs and personal interviews was carried out in 36 study centres in 19 European countries on a total of 15,570 men and women aged 50-79 years (population-based stratified random samples). No interventions were done. The main outcome measures were the presence and intensity of current and previous back pain, functional capacity (ADL questionnaire) and overall subjective health. The presence and intensity of back pain and functional and health impairments varied within wide ranges with no obvious regional pattern. However, the associations between negative health outcomes and vertebral deformity were homogeneous between countries and between centres within countries. In logistic regression analyses weak but significant associations between the presence of vertebral deformities and various health indicators were demonstrated. The magnitude of the associations increased with severity and number of deformities. Compared with subjects without deformities those with low-grade deformities had no or only a weakly elevated risk for back pain, disability and impaired subjective health (odds ratios (OR) 1.2-1.3). The odds ratios increased for individuals with single severe deformities (OR 1.3-2.1) and were highest in those with multiple severe deformities (OR 1.7-4.2). The associations between vertebral deformities and negative health outcomes were stronger in men than in women. In this cross-sectional study radiologically assessed vertebral deformities were therefore weakly associated with both current and previous back pain as well as with functional and health impairments in both women and men. Multiple severe deformities were associated with severe and disabling back pain with stronger effects in men.

Original languageEnglish
Pages (from-to)364-372
Number of pages9
JournalOsteoporosis International
Volume8
Issue number4
DOIs
Publication statusPublished - 1998

Fingerprint

Back Pain
Osteoporosis
Diagnostic Self Evaluation
Health
Odds Ratio
Cross-Sectional Studies
Activities of Daily Living
Logistic Models
Regression Analysis
Outcome Assessment (Health Care)
Interviews
Population

Keywords

  • Back pain
  • Impaired function
  • Osteoporosis
  • Subjective health
  • Vertebral deformities

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Matthis, C., Weber, U., O'Neill, T. W., Raspe, H., Agnusdei, D., Bergmann, K., ... Woolf, A. D. (1998). Health impact associated with vertebral deformities: Results from the european vertebral osteoporosis study (EVOS). Osteoporosis International, 8(4), 364-372. https://doi.org/10.1007/s001980050076

Health impact associated with vertebral deformities : Results from the european vertebral osteoporosis study (EVOS). / Matthis, C.; Weber, U.; O'Neill, T. W.; Raspe, H.; Agnusdei, D.; Bergmann, K.; Cooper, C.; Dequeker, J.; Felsenberg, D.; Kanis, J. A.; Kruskemper, G.; Raspe, H.; Silman, A. J.; Felsenberg, D.; Wieland, E. H.; Kalidis, L.; Lauermann, T.; Weber, K.; Geusens, P.; Jajic, I.; Havelka, S.; Vavrincova, P.; Delmas, P. D.; Marchand, F.; Banzer, D.; Kirschner, S.; Reisinger, W.; Janot, J.; Schatz, H.; Franke, J.; Scheidt-Nave, C.; Ziegler, R.; Abendroth, K.; Felsch, B.; Antoniou, A.; Lyritis, G.; Kiss, C.; Poor, G.; Ortolani, S.; Agnusdei, D.; Gennari, C.; Hofman, A.; Pols, H. A P; Falch, J. A.; Meyer, H. E.; Czekalski, S.; Miazgowski, T.; Hoszowski, K.; Lorenc, R. S.; Aroso, A.; Lopez, A.; Benevolenskaya, L. I.; Mikhailov, E. E.; Letkovska, A.; Masaryk, P.; Roig Escofet, D.; Ruiz Martin, M.; Sosa, M.; Diaz Curiel, M.; Rapado, A.; Cannata Andia, J. B.; Diaz Lopez, J. B.; Johnell, O.; Nilsson, B.; Dilsen, G.; Reid, D. M.; Bhalla, A. K.; Ring, F.; Todd, C.; Williams, R.; Reeve, J.; Eastell, R.; Woolf, A. D.

In: Osteoporosis International, Vol. 8, No. 4, 1998, p. 364-372.

Research output: Contribution to journalArticle

Matthis, C, Weber, U, O'Neill, TW, Raspe, H, Agnusdei, D, Bergmann, K, Cooper, C, Dequeker, J, Felsenberg, D, Kanis, JA, Kruskemper, G, Raspe, H, Silman, AJ, Felsenberg, D, Wieland, EH, Kalidis, L, Lauermann, T, Weber, K, Geusens, P, Jajic, I, Havelka, S, Vavrincova, P, Delmas, PD, Marchand, F, Banzer, D, Kirschner, S, Reisinger, W, Janot, J, Schatz, H, Franke, J, Scheidt-Nave, C, Ziegler, R, Abendroth, K, Felsch, B, Antoniou, A, Lyritis, G, Kiss, C, Poor, G, Ortolani, S, Agnusdei, D, Gennari, C, Hofman, A, Pols, HAP, Falch, JA, Meyer, HE, Czekalski, S, Miazgowski, T, Hoszowski, K, Lorenc, RS, Aroso, A, Lopez, A, Benevolenskaya, LI, Mikhailov, EE, Letkovska, A, Masaryk, P, Roig Escofet, D, Ruiz Martin, M, Sosa, M, Diaz Curiel, M, Rapado, A, Cannata Andia, JB, Diaz Lopez, JB, Johnell, O, Nilsson, B, Dilsen, G, Reid, DM, Bhalla, AK, Ring, F, Todd, C, Williams, R, Reeve, J, Eastell, R & Woolf, AD 1998, 'Health impact associated with vertebral deformities: Results from the european vertebral osteoporosis study (EVOS)', Osteoporosis International, vol. 8, no. 4, pp. 364-372. https://doi.org/10.1007/s001980050076
Matthis, C. ; Weber, U. ; O'Neill, T. W. ; Raspe, H. ; Agnusdei, D. ; Bergmann, K. ; Cooper, C. ; Dequeker, J. ; Felsenberg, D. ; Kanis, J. A. ; Kruskemper, G. ; Raspe, H. ; Silman, A. J. ; Felsenberg, D. ; Wieland, E. H. ; Kalidis, L. ; Lauermann, T. ; Weber, K. ; Geusens, P. ; Jajic, I. ; Havelka, S. ; Vavrincova, P. ; Delmas, P. D. ; Marchand, F. ; Banzer, D. ; Kirschner, S. ; Reisinger, W. ; Janot, J. ; Schatz, H. ; Franke, J. ; Scheidt-Nave, C. ; Ziegler, R. ; Abendroth, K. ; Felsch, B. ; Antoniou, A. ; Lyritis, G. ; Kiss, C. ; Poor, G. ; Ortolani, S. ; Agnusdei, D. ; Gennari, C. ; Hofman, A. ; Pols, H. A P ; Falch, J. A. ; Meyer, H. E. ; Czekalski, S. ; Miazgowski, T. ; Hoszowski, K. ; Lorenc, R. S. ; Aroso, A. ; Lopez, A. ; Benevolenskaya, L. I. ; Mikhailov, E. E. ; Letkovska, A. ; Masaryk, P. ; Roig Escofet, D. ; Ruiz Martin, M. ; Sosa, M. ; Diaz Curiel, M. ; Rapado, A. ; Cannata Andia, J. B. ; Diaz Lopez, J. B. ; Johnell, O. ; Nilsson, B. ; Dilsen, G. ; Reid, D. M. ; Bhalla, A. K. ; Ring, F. ; Todd, C. ; Williams, R. ; Reeve, J. ; Eastell, R. ; Woolf, A. D. / Health impact associated with vertebral deformities : Results from the european vertebral osteoporosis study (EVOS). In: Osteoporosis International. 1998 ; Vol. 8, No. 4. pp. 364-372.
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TY - JOUR

T1 - Health impact associated with vertebral deformities

T2 - Results from the european vertebral osteoporosis study (EVOS)

AU - Matthis, C.

AU - Weber, U.

AU - O'Neill, T. W.

AU - Raspe, H.

AU - Agnusdei, D.

AU - Bergmann, K.

AU - Cooper, C.

AU - Dequeker, J.

AU - Felsenberg, D.

AU - Kanis, J. A.

AU - Kruskemper, G.

AU - Raspe, H.

AU - Silman, A. J.

AU - Felsenberg, D.

AU - Wieland, E. H.

AU - Kalidis, L.

AU - Lauermann, T.

AU - Weber, K.

AU - Geusens, P.

AU - Jajic, I.

AU - Havelka, S.

AU - Vavrincova, P.

AU - Delmas, P. D.

AU - Marchand, F.

AU - Banzer, D.

AU - Kirschner, S.

AU - Reisinger, W.

AU - Janot, J.

AU - Schatz, H.

AU - Franke, J.

AU - Scheidt-Nave, C.

AU - Ziegler, R.

AU - Abendroth, K.

AU - Felsch, B.

AU - Antoniou, A.

AU - Lyritis, G.

AU - Kiss, C.

AU - Poor, G.

AU - Ortolani, S.

AU - Agnusdei, D.

AU - Gennari, C.

AU - Hofman, A.

AU - Pols, H. A P

AU - Falch, J. A.

AU - Meyer, H. E.

AU - Czekalski, S.

AU - Miazgowski, T.

AU - Hoszowski, K.

AU - Lorenc, R. S.

AU - Aroso, A.

AU - Lopez, A.

AU - Benevolenskaya, L. I.

AU - Mikhailov, E. E.

AU - Letkovska, A.

AU - Masaryk, P.

AU - Roig Escofet, D.

AU - Ruiz Martin, M.

AU - Sosa, M.

AU - Diaz Curiel, M.

AU - Rapado, A.

AU - Cannata Andia, J. B.

AU - Diaz Lopez, J. B.

AU - Johnell, O.

AU - Nilsson, B.

AU - Dilsen, G.

AU - Reid, D. M.

AU - Bhalla, A. K.

AU - Ring, F.

AU - Todd, C.

AU - Williams, R.

AU - Reeve, J.

AU - Eastell, R.

AU - Woolf, A. D.

PY - 1998

Y1 - 1998

N2 - To study the association between vertebral deformities and subjective health outcome indicators, including back pain and disability, a cross-sectional survey with spinal radiographs and personal interviews was carried out in 36 study centres in 19 European countries on a total of 15,570 men and women aged 50-79 years (population-based stratified random samples). No interventions were done. The main outcome measures were the presence and intensity of current and previous back pain, functional capacity (ADL questionnaire) and overall subjective health. The presence and intensity of back pain and functional and health impairments varied within wide ranges with no obvious regional pattern. However, the associations between negative health outcomes and vertebral deformity were homogeneous between countries and between centres within countries. In logistic regression analyses weak but significant associations between the presence of vertebral deformities and various health indicators were demonstrated. The magnitude of the associations increased with severity and number of deformities. Compared with subjects without deformities those with low-grade deformities had no or only a weakly elevated risk for back pain, disability and impaired subjective health (odds ratios (OR) 1.2-1.3). The odds ratios increased for individuals with single severe deformities (OR 1.3-2.1) and were highest in those with multiple severe deformities (OR 1.7-4.2). The associations between vertebral deformities and negative health outcomes were stronger in men than in women. In this cross-sectional study radiologically assessed vertebral deformities were therefore weakly associated with both current and previous back pain as well as with functional and health impairments in both women and men. Multiple severe deformities were associated with severe and disabling back pain with stronger effects in men.

AB - To study the association between vertebral deformities and subjective health outcome indicators, including back pain and disability, a cross-sectional survey with spinal radiographs and personal interviews was carried out in 36 study centres in 19 European countries on a total of 15,570 men and women aged 50-79 years (population-based stratified random samples). No interventions were done. The main outcome measures were the presence and intensity of current and previous back pain, functional capacity (ADL questionnaire) and overall subjective health. The presence and intensity of back pain and functional and health impairments varied within wide ranges with no obvious regional pattern. However, the associations between negative health outcomes and vertebral deformity were homogeneous between countries and between centres within countries. In logistic regression analyses weak but significant associations between the presence of vertebral deformities and various health indicators were demonstrated. The magnitude of the associations increased with severity and number of deformities. Compared with subjects without deformities those with low-grade deformities had no or only a weakly elevated risk for back pain, disability and impaired subjective health (odds ratios (OR) 1.2-1.3). The odds ratios increased for individuals with single severe deformities (OR 1.3-2.1) and were highest in those with multiple severe deformities (OR 1.7-4.2). The associations between vertebral deformities and negative health outcomes were stronger in men than in women. In this cross-sectional study radiologically assessed vertebral deformities were therefore weakly associated with both current and previous back pain as well as with functional and health impairments in both women and men. Multiple severe deformities were associated with severe and disabling back pain with stronger effects in men.

KW - Back pain

KW - Impaired function

KW - Osteoporosis

KW - Subjective health

KW - Vertebral deformities

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