Health related quality of life after radical cystectomy: Comparison of ileal conduit to continent orthotopic neobladder

R. Autorino, G. Quarto, G. Di Lorenzo, M. De Sio, S. Perdonà, G. Giannarini, F. Giugliano, R. Damiano

Research output: Contribution to journalArticlepeer-review


Aims: To compare health related quality of life (HRQOL) between patients with two different types of urinary diversion, ileal conduit and orthotopic neobladder, and between them and an age-matched population of healthy subjects. Materials and methods: Eighty eight patients treated with radical cystectomy for bladder cancer at our institutions between 2002 and 2007 were contacted for this survey. All of them had a follow-up of more than 12 months after surgery and were recurrence free. The SF-36 questionnaire was provided to each patient during a follow-up visit at outpatient clinics. Overall, 79 patients (90%) returned the questionnaire and were included in this analysis. They were divided into two groups: group 1 comprised 44 patients with an ileal conduit diversion, and group 2 included 35 patients with a neobladder. As a control, normative values of an age-matched healthy Italian population were considered. Results: No significant difference was found in scale scores between the neobladder and ileal conduit groups. Scale scores for role-physical functioning, social functioning and role-emotional functioning in both the neobladder and ileal conduit groups were significantly below the Italian population norm. Patients with a neobladder 65 years old or older (n = 18) had significantly lower scores for role-physical functioning and role-emotional functioning than those younger than 65 years (n = 17; p <0.05). Conclusion: Few differences between ileal conduit and orthotopic bladder substitution have been detected. Thus, the assumption that continent reconstruction provides better HRQOL than ileal conduit diversion cannot be supported. Patient education and active participation in treatment decisions seem to be the key to postoperative satisfaction.

Original languageEnglish
Pages (from-to)858-864
Number of pages7
JournalEuropean Journal of Surgical Oncology
Issue number8
Publication statusPublished - Aug 2009


  • Bladder cancer
  • Ileal conduit
  • Orthotopic neobladder
  • Quality of life
  • Radical cystectomy
  • SF-36

ASJC Scopus subject areas

  • Oncology
  • Surgery


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