Health-related quality of life assessment in young adults with seasonal allergic rhinitis

Giuseppina Majani, I. Biardini, A. Giardini, G. E. Senna, P. Minale, S. D'Ulisse, G. Ciprandi, W. Canonica

Research output: Contribution to journalArticlepeer-review


Background: In health-related quality of life (HRQL) studies on allergic rhinitis, both disease-specific and generic questionnaires have been extensively used. Seasonal allergic rhinitis (SAR) has been studied mainly by focusing on symptomatology. The present study aimed to evaluate the SAR-HRQL by means of two questionnaires, the Medical Outcome Study Short Form Health Survey (SF-36) and a new instrument examining satisfaction in 32 aspects of daily life: the Satisfaction Profile (SAT-P). Methods: Thirty-three patients with SAR (aged 33.5±8.5 years; 12 men, 21 women) were evaluated during and 2 months after the pollen season. Data were compared with reference samples by t-test, and baseline and follow-up HRQL scores were compared by a matched-pair test. Results: Patients' HRQL scores collected during the pollen season were significantly lower than reference sample data in many SF-36 scores and in one SAT-P item. No differences emerged between SF-36 and SAT-P scores collected outside the pollen season and reference sample scores. Compared to baseline, outside the pollen season, patients reported significantly higher scores in the following SF-36 scales: physical functioning (P = 0.002), physical role (P = 0.00001), bodily pain (P = 0.01), and vitality (P = 0.008); and significantly higher scores in only two SAT-P items (physical well-being [P = 0.009] and resistance to stress [P = 0.01]). Conclusions: Our data confirm the utility of using symptomatologic and health-status questionnaires in evaluating the HRQL of SAR patients. More general quality of life questionnaires may prevent the symptomatologic and functional problems from being adequately recognized and managed. SAT-P can be a fruitful additional tool in HRQL evaluation.

Original languageEnglish
Pages (from-to)313-317
Number of pages5
JournalAllergy: European Journal of Allergy and Clinical Immunology
Issue number4
Publication statusPublished - 2001


  • Generic questionnaire
  • Quality of life
  • Satisfaction profile
  • Seasonal allergic rhinitis

ASJC Scopus subject areas

  • Immunology


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