Health-related quality of life measures and psychiatric comorbidity in patients with migraine

M. Mula, M. Viana, R. Jauch, B. Schmitz, D. Bettucci, A. E. Cavanna, G. Strigaro, M. G. Tota, H. Israel, U. Reuter, F. Monaco

Research output: Contribution to journalArticle

Abstract

Background and purpose: The identification of factors associated to health-related quality of life (HRQoL) measures in patients with migraine has major implications in terms of prognosis and treatment. This study aimed at investigating associations between HRQoL and comorbid mood and anxiety disorders. Methods: Consecutive adult outpatients with a diagnosis of migraine with or without aura were assessed using the Mini International Neuropsychiatric Interview (M.I.N.I.) Plus version 5.0.0 and the Migraine-Specific Quality-of-Life Questionnaire (MSQ). Results: Data of 112 patients (82 females), 69 without aura, mean age 41.2 ± 13.3 years were analyzed. According to the M.I.N.I., 50% patients had a lifetime or current DSM-IV diagnosis of mood or anxiety disorder. There was no between-groups difference in MSQ total and subscale scores in relation to the presence/absence of psychiatric comorbidity, independently whether that was current or lifetime. In the group of subjects with psychiatric disorders, age at onset of migraine correlated with MSQ-total (rho = -0.407 P = 0.002), and subscale scores (Role Function-Restrictive, rho = -0.397, P = 0.002; Emotional Function, rho = -0.487, P <0.001). Conclusions: Our findings suggest that current and/or lifetime psychiatric comorbidities are not associated with HRQoL measures in patients with migraine. However, patients with migraine and psychiatric comorbidities may represent a specific subgroup deserving particular attention for targeted interventions.

Original languageEnglish
Pages (from-to)1017-1021
Number of pages5
JournalEuropean Journal of Neurology
Volume16
Issue number9
DOIs
Publication statusPublished - Sep 2009

Fingerprint

Migraine Disorders
Psychiatry
Comorbidity
Quality of Life
Anxiety Disorders
Mood Disorders
Migraine without Aura
Migraine with Aura
Age of Onset
Diagnostic and Statistical Manual of Mental Disorders
Epilepsy
Outpatients
Interviews
Therapeutics

Keywords

  • Anxiety
  • Depression
  • Migraine
  • Psychiatric comorbidity
  • Quality of life

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Mula, M., Viana, M., Jauch, R., Schmitz, B., Bettucci, D., Cavanna, A. E., ... Monaco, F. (2009). Health-related quality of life measures and psychiatric comorbidity in patients with migraine. European Journal of Neurology, 16(9), 1017-1021. https://doi.org/10.1111/j.1468-1331.2009.02636.x

Health-related quality of life measures and psychiatric comorbidity in patients with migraine. / Mula, M.; Viana, M.; Jauch, R.; Schmitz, B.; Bettucci, D.; Cavanna, A. E.; Strigaro, G.; Tota, M. G.; Israel, H.; Reuter, U.; Monaco, F.

In: European Journal of Neurology, Vol. 16, No. 9, 09.2009, p. 1017-1021.

Research output: Contribution to journalArticle

Mula, M, Viana, M, Jauch, R, Schmitz, B, Bettucci, D, Cavanna, AE, Strigaro, G, Tota, MG, Israel, H, Reuter, U & Monaco, F 2009, 'Health-related quality of life measures and psychiatric comorbidity in patients with migraine', European Journal of Neurology, vol. 16, no. 9, pp. 1017-1021. https://doi.org/10.1111/j.1468-1331.2009.02636.x
Mula, M. ; Viana, M. ; Jauch, R. ; Schmitz, B. ; Bettucci, D. ; Cavanna, A. E. ; Strigaro, G. ; Tota, M. G. ; Israel, H. ; Reuter, U. ; Monaco, F. / Health-related quality of life measures and psychiatric comorbidity in patients with migraine. In: European Journal of Neurology. 2009 ; Vol. 16, No. 9. pp. 1017-1021.
@article{3d8755607d12484ca07a0140ae6361bb,
title = "Health-related quality of life measures and psychiatric comorbidity in patients with migraine",
abstract = "Background and purpose: The identification of factors associated to health-related quality of life (HRQoL) measures in patients with migraine has major implications in terms of prognosis and treatment. This study aimed at investigating associations between HRQoL and comorbid mood and anxiety disorders. Methods: Consecutive adult outpatients with a diagnosis of migraine with or without aura were assessed using the Mini International Neuropsychiatric Interview (M.I.N.I.) Plus version 5.0.0 and the Migraine-Specific Quality-of-Life Questionnaire (MSQ). Results: Data of 112 patients (82 females), 69 without aura, mean age 41.2 ± 13.3 years were analyzed. According to the M.I.N.I., 50{\%} patients had a lifetime or current DSM-IV diagnosis of mood or anxiety disorder. There was no between-groups difference in MSQ total and subscale scores in relation to the presence/absence of psychiatric comorbidity, independently whether that was current or lifetime. In the group of subjects with psychiatric disorders, age at onset of migraine correlated with MSQ-total (rho = -0.407 P = 0.002), and subscale scores (Role Function-Restrictive, rho = -0.397, P = 0.002; Emotional Function, rho = -0.487, P <0.001). Conclusions: Our findings suggest that current and/or lifetime psychiatric comorbidities are not associated with HRQoL measures in patients with migraine. However, patients with migraine and psychiatric comorbidities may represent a specific subgroup deserving particular attention for targeted interventions.",
keywords = "Anxiety, Depression, Migraine, Psychiatric comorbidity, Quality of life",
author = "M. Mula and M. Viana and R. Jauch and B. Schmitz and D. Bettucci and Cavanna, {A. E.} and G. Strigaro and Tota, {M. G.} and H. Israel and U. Reuter and F. Monaco",
year = "2009",
month = "9",
doi = "10.1111/j.1468-1331.2009.02636.x",
language = "English",
volume = "16",
pages = "1017--1021",
journal = "European Journal of Neurology",
issn = "1351-5101",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "9",

}

TY - JOUR

T1 - Health-related quality of life measures and psychiatric comorbidity in patients with migraine

AU - Mula, M.

AU - Viana, M.

AU - Jauch, R.

AU - Schmitz, B.

AU - Bettucci, D.

AU - Cavanna, A. E.

AU - Strigaro, G.

AU - Tota, M. G.

AU - Israel, H.

AU - Reuter, U.

AU - Monaco, F.

PY - 2009/9

Y1 - 2009/9

N2 - Background and purpose: The identification of factors associated to health-related quality of life (HRQoL) measures in patients with migraine has major implications in terms of prognosis and treatment. This study aimed at investigating associations between HRQoL and comorbid mood and anxiety disorders. Methods: Consecutive adult outpatients with a diagnosis of migraine with or without aura were assessed using the Mini International Neuropsychiatric Interview (M.I.N.I.) Plus version 5.0.0 and the Migraine-Specific Quality-of-Life Questionnaire (MSQ). Results: Data of 112 patients (82 females), 69 without aura, mean age 41.2 ± 13.3 years were analyzed. According to the M.I.N.I., 50% patients had a lifetime or current DSM-IV diagnosis of mood or anxiety disorder. There was no between-groups difference in MSQ total and subscale scores in relation to the presence/absence of psychiatric comorbidity, independently whether that was current or lifetime. In the group of subjects with psychiatric disorders, age at onset of migraine correlated with MSQ-total (rho = -0.407 P = 0.002), and subscale scores (Role Function-Restrictive, rho = -0.397, P = 0.002; Emotional Function, rho = -0.487, P <0.001). Conclusions: Our findings suggest that current and/or lifetime psychiatric comorbidities are not associated with HRQoL measures in patients with migraine. However, patients with migraine and psychiatric comorbidities may represent a specific subgroup deserving particular attention for targeted interventions.

AB - Background and purpose: The identification of factors associated to health-related quality of life (HRQoL) measures in patients with migraine has major implications in terms of prognosis and treatment. This study aimed at investigating associations between HRQoL and comorbid mood and anxiety disorders. Methods: Consecutive adult outpatients with a diagnosis of migraine with or without aura were assessed using the Mini International Neuropsychiatric Interview (M.I.N.I.) Plus version 5.0.0 and the Migraine-Specific Quality-of-Life Questionnaire (MSQ). Results: Data of 112 patients (82 females), 69 without aura, mean age 41.2 ± 13.3 years were analyzed. According to the M.I.N.I., 50% patients had a lifetime or current DSM-IV diagnosis of mood or anxiety disorder. There was no between-groups difference in MSQ total and subscale scores in relation to the presence/absence of psychiatric comorbidity, independently whether that was current or lifetime. In the group of subjects with psychiatric disorders, age at onset of migraine correlated with MSQ-total (rho = -0.407 P = 0.002), and subscale scores (Role Function-Restrictive, rho = -0.397, P = 0.002; Emotional Function, rho = -0.487, P <0.001). Conclusions: Our findings suggest that current and/or lifetime psychiatric comorbidities are not associated with HRQoL measures in patients with migraine. However, patients with migraine and psychiatric comorbidities may represent a specific subgroup deserving particular attention for targeted interventions.

KW - Anxiety

KW - Depression

KW - Migraine

KW - Psychiatric comorbidity

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=68849120962&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68849120962&partnerID=8YFLogxK

U2 - 10.1111/j.1468-1331.2009.02636.x

DO - 10.1111/j.1468-1331.2009.02636.x

M3 - Article

C2 - 19473352

AN - SCOPUS:68849120962

VL - 16

SP - 1017

EP - 1021

JO - European Journal of Neurology

JF - European Journal of Neurology

SN - 1351-5101

IS - 9

ER -