Hearing loss and changes in transient evoked otoacoustic emissions after gamma knife radiosurgery for acoustic neurinomas

Francesco Ottaviani, Cesare Bartolomeo Neglia, Laura Ventrella, Enrico Giugni, Enrico Motti

Research output: Contribution to journalArticle


Objective: To evaluate the neuro-otological effects of gamma knife radiosurgery in patients with acoustic neurinoma. Design: Prospective study. Setting: University hospital in Milan, Italy. Patients: Thirty consecutive patients with acoustic neurinoma who underwent gamma knife radiosurgery. Intervention: Gamma knife radiosurgery. Main Outcome Measures: Results of neurootological tests, including pure-tone audiometry, auditory brainstem responses, and transient evoked otoacoustic emissions, during a 2-year follow-up. Results: Three patients showed slight tumor growth, 1 complained of a transient facial disturbance, and 5 complained of mild trigeminal disturbances. Seven of the 26 patients with a measurable threshold before radiosurgery experienced a 2-year decrease of more than 20 dB in at least 1 hearing level, and 2 of these became deaf in the affected ear. The analysis of auditory brainstem responses showed no significant increase in mean wave V latency after radiosurgery, but intensity of transient evoked otoacoustic emissions worsened in 9 of the 12 patients who had them before treatment. A statistically significant correlation was found between the 2-year decrease in lowtone average, pure-tone average, and high-tone average hearing levels and the 2-year decrease in transient evoked oacoustic emissions (P

Original languageEnglish
Pages (from-to)1308-1312
Number of pages5
JournalArchives of Otolaryngology - Head and Neck Surgery
Issue number11
Publication statusPublished - Nov 1 2002


ASJC Scopus subject areas

  • Otorhinolaryngology

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