Abstract
Background: During atrial fibrillation (AF), ventricular response is highly irregular and thus the beat-to-beat variation of blood pressure is increased because of variations in filling time and in contractility. Objectives: Aim of the present study is to investigate the short-term dynamics of RR and SAP series in patients with AF, during rest and tilt, and after restoration of sinus rhythm. Methods: We computed symbolic sequences of the three phases, as they retain important features of the dynamics generated by the underlying control system. Then we applied a method based on rank order statistics of symbolic sequences to investigate the profile of different types of dynamics. The linguistic distance (range 0-1) between sequences represents a measure of similarity to assess whether the different physiological states are reflected on the dynamics of RR and SAP series. Results: The distance between rest and tilt phases is 0.06 ± 0.02 for RR series, meaning they are very similar, while it is 0.21 ± 0.13 for SAP series, showing a difference in the shortterm dynamics. RR mean decreases during tilt (738 ± 164 vs. 692 ± 152 ms, p <0.05, rest vs. tilt), while mean SAP is not significantly different (101 ± 20 vs. 104 ± 14 mmHg, rest vs. tilt). Comparing AF and sinus rhythm, both RR and SAP series result different in terms of the computed distance. Conclusions: SAP short-term dynamics seem to significantly change when comparing rest and tilt phases, while RR series remain unchanged. Moreover, RR mean but not SAP series significantly decreases during tilt.
| Original language | English |
|---|---|
| Pages (from-to) | 516-520 |
| Number of pages | 5 |
| Journal | Methods of Information in Medicine |
| Volume | 49 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2010 |
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Keywords
- Atrial fibrillation
- Blood pressure
- Degree of nonrandomness
- Heart rate variability
- Linguistic analysis
ASJC Scopus subject areas
- Health Informatics
- Health Information Management
- Advanced and Specialised Nursing
Cite this
Heart rate and systolic blood pressure in patients with persistent atrial fibrillation : A linguistic analysis. / Corino, V. D A; Belletti, S.; Terranova, P.; Lombardi, F.; Mainardi, L. T.
In: Methods of Information in Medicine, Vol. 49, No. 5, 2010, p. 516-520.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Heart rate and systolic blood pressure in patients with persistent atrial fibrillation
T2 - A linguistic analysis
AU - Corino, V. D A
AU - Belletti, S.
AU - Terranova, P.
AU - Lombardi, F.
AU - Mainardi, L. T.
PY - 2010
Y1 - 2010
N2 - Background: During atrial fibrillation (AF), ventricular response is highly irregular and thus the beat-to-beat variation of blood pressure is increased because of variations in filling time and in contractility. Objectives: Aim of the present study is to investigate the short-term dynamics of RR and SAP series in patients with AF, during rest and tilt, and after restoration of sinus rhythm. Methods: We computed symbolic sequences of the three phases, as they retain important features of the dynamics generated by the underlying control system. Then we applied a method based on rank order statistics of symbolic sequences to investigate the profile of different types of dynamics. The linguistic distance (range 0-1) between sequences represents a measure of similarity to assess whether the different physiological states are reflected on the dynamics of RR and SAP series. Results: The distance between rest and tilt phases is 0.06 ± 0.02 for RR series, meaning they are very similar, while it is 0.21 ± 0.13 for SAP series, showing a difference in the shortterm dynamics. RR mean decreases during tilt (738 ± 164 vs. 692 ± 152 ms, p <0.05, rest vs. tilt), while mean SAP is not significantly different (101 ± 20 vs. 104 ± 14 mmHg, rest vs. tilt). Comparing AF and sinus rhythm, both RR and SAP series result different in terms of the computed distance. Conclusions: SAP short-term dynamics seem to significantly change when comparing rest and tilt phases, while RR series remain unchanged. Moreover, RR mean but not SAP series significantly decreases during tilt.
AB - Background: During atrial fibrillation (AF), ventricular response is highly irregular and thus the beat-to-beat variation of blood pressure is increased because of variations in filling time and in contractility. Objectives: Aim of the present study is to investigate the short-term dynamics of RR and SAP series in patients with AF, during rest and tilt, and after restoration of sinus rhythm. Methods: We computed symbolic sequences of the three phases, as they retain important features of the dynamics generated by the underlying control system. Then we applied a method based on rank order statistics of symbolic sequences to investigate the profile of different types of dynamics. The linguistic distance (range 0-1) between sequences represents a measure of similarity to assess whether the different physiological states are reflected on the dynamics of RR and SAP series. Results: The distance between rest and tilt phases is 0.06 ± 0.02 for RR series, meaning they are very similar, while it is 0.21 ± 0.13 for SAP series, showing a difference in the shortterm dynamics. RR mean decreases during tilt (738 ± 164 vs. 692 ± 152 ms, p <0.05, rest vs. tilt), while mean SAP is not significantly different (101 ± 20 vs. 104 ± 14 mmHg, rest vs. tilt). Comparing AF and sinus rhythm, both RR and SAP series result different in terms of the computed distance. Conclusions: SAP short-term dynamics seem to significantly change when comparing rest and tilt phases, while RR series remain unchanged. Moreover, RR mean but not SAP series significantly decreases during tilt.
KW - Atrial fibrillation
KW - Blood pressure
KW - Degree of nonrandomness
KW - Heart rate variability
KW - Linguistic analysis
UR - http://www.scopus.com/inward/record.url?scp=79952279558&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952279558&partnerID=8YFLogxK
U2 - 10.3414/ME09-02-0035
DO - 10.3414/ME09-02-0035
M3 - Article
C2 - 20526522
AN - SCOPUS:79952279558
VL - 49
SP - 516
EP - 520
JO - Methods of Information in Medicine
JF - Methods of Information in Medicine
SN - 0026-1270
IS - 5
ER -