Heart rate variability as a clinical tool

Alberto Malliani, Nicola Montano

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Power spectrum analysis of cardiovascular signal variability, and in particular of the RR period (heart rate variability), is a widely used procedure for the investigation of autonomic cardiovascular control and/or target function impairment. However, a correct methodology is essential to extract the information embedded in the frequency domain. This article has the main purpose of proposing a still wider clinical use of the spectral methodology. Indeed, with this procedure the state of the sympathovagal balance modulating the sinus node pacemaker activity can be quantified in a variety of physiological and pathophysiological conditions. Changes in the sympathovagal balance can be often detected in basal conditions; however, a reduced responsiveness to an excitatory stimulus is the most common feature that characterizes numerous pathophysiological states. Moreover, the attenuation of an oscillatory pattern or its impaired responsiveness to a given stimulus can also reflect an altered target function and thus can furnish interesting prognostic markers.

Original languageEnglish
Pages (from-to)439-445
Number of pages7
JournalItalian Heart Journal
Volume3
Issue number8
Publication statusPublished - Aug 1 2002

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Heart Rate
Sinoatrial Node
Spectrum Analysis

Keywords

  • Autonomic nervous system
  • Spectral analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Heart rate variability as a clinical tool. / Malliani, Alberto; Montano, Nicola.

In: Italian Heart Journal, Vol. 3, No. 8, 01.08.2002, p. 439-445.

Research output: Contribution to journalArticle

Malliani, A & Montano, N 2002, 'Heart rate variability as a clinical tool', Italian Heart Journal, vol. 3, no. 8, pp. 439-445.
Malliani, Alberto ; Montano, Nicola. / Heart rate variability as a clinical tool. In: Italian Heart Journal. 2002 ; Vol. 3, No. 8. pp. 439-445.
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