Abstract
Mitral valve prolapse (MVP) is a common valvular abnormality especially in young female subjects. Recently, Boudulas had classified the patients with MVP into two types: the 1st type is MVP-anatomic (MVPa) with valvular malfunction and the 2nd MVP-syndrome (MVPs) without valvular disease. In the 2nd type, several authors have reported the occurrence of functional abnormalities of neuroendocrine or autonomic systems. Also, the syncope called 'neuromediated' has been found and is probably associated with modification of the autonomic nervous system. To understand the role of the autonomic nervous system, 39 female patients with MVPs (group 1) and 24 normal females as control group (group 2) were evaluated by a spectral analysis of heart rate variability (HRV) in time and frequency domains. The analysis between the two groups showed a low vagal tone in group 1 resulting in a lower high-frequency normalized unit (HF-NU) in comparison with the control group 2 (p <0.03). Group 1 was divided into two subgroups with and without syncope. The analysis of HRV by Anova indicated no differences for all parameters between the two subgroups of MVPs patients. These results demonstrate that (1) MVPs has a low vagal tone; (2) the syncope in MVPs could not be only in relation to the autonomic nervous system malfunction, but probably other causes underlined this phenomenon.
| Original language | English |
|---|---|
| Pages (from-to) | 210-214 |
| Number of pages | 5 |
| Journal | American Journal of Noninvasive Cardiology |
| Volume | 7 |
| Issue number | 4 |
| Publication status | Published - 1993 |
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Keywords
- Echo-Doppler
- Heart rate variability
- Mitral valve prolapse
- Syncope
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Heart rate variability assessment in patients with mitral valve prolapse syndrome. / Marangoni, S.; Scalvini, S.; Mai, R.; Quadri, A.; Levi, G. F.
In: American Journal of Noninvasive Cardiology, Vol. 7, No. 4, 1993, p. 210-214.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Heart rate variability assessment in patients with mitral valve prolapse syndrome
AU - Marangoni, S.
AU - Scalvini, S.
AU - Mai, R.
AU - Quadri, A.
AU - Levi, G. F.
PY - 1993
Y1 - 1993
N2 - Mitral valve prolapse (MVP) is a common valvular abnormality especially in young female subjects. Recently, Boudulas had classified the patients with MVP into two types: the 1st type is MVP-anatomic (MVPa) with valvular malfunction and the 2nd MVP-syndrome (MVPs) without valvular disease. In the 2nd type, several authors have reported the occurrence of functional abnormalities of neuroendocrine or autonomic systems. Also, the syncope called 'neuromediated' has been found and is probably associated with modification of the autonomic nervous system. To understand the role of the autonomic nervous system, 39 female patients with MVPs (group 1) and 24 normal females as control group (group 2) were evaluated by a spectral analysis of heart rate variability (HRV) in time and frequency domains. The analysis between the two groups showed a low vagal tone in group 1 resulting in a lower high-frequency normalized unit (HF-NU) in comparison with the control group 2 (p <0.03). Group 1 was divided into two subgroups with and without syncope. The analysis of HRV by Anova indicated no differences for all parameters between the two subgroups of MVPs patients. These results demonstrate that (1) MVPs has a low vagal tone; (2) the syncope in MVPs could not be only in relation to the autonomic nervous system malfunction, but probably other causes underlined this phenomenon.
AB - Mitral valve prolapse (MVP) is a common valvular abnormality especially in young female subjects. Recently, Boudulas had classified the patients with MVP into two types: the 1st type is MVP-anatomic (MVPa) with valvular malfunction and the 2nd MVP-syndrome (MVPs) without valvular disease. In the 2nd type, several authors have reported the occurrence of functional abnormalities of neuroendocrine or autonomic systems. Also, the syncope called 'neuromediated' has been found and is probably associated with modification of the autonomic nervous system. To understand the role of the autonomic nervous system, 39 female patients with MVPs (group 1) and 24 normal females as control group (group 2) were evaluated by a spectral analysis of heart rate variability (HRV) in time and frequency domains. The analysis between the two groups showed a low vagal tone in group 1 resulting in a lower high-frequency normalized unit (HF-NU) in comparison with the control group 2 (p <0.03). Group 1 was divided into two subgroups with and without syncope. The analysis of HRV by Anova indicated no differences for all parameters between the two subgroups of MVPs patients. These results demonstrate that (1) MVPs has a low vagal tone; (2) the syncope in MVPs could not be only in relation to the autonomic nervous system malfunction, but probably other causes underlined this phenomenon.
KW - Echo-Doppler
KW - Heart rate variability
KW - Mitral valve prolapse
KW - Syncope
UR - http://www.scopus.com/inward/record.url?scp=0027434089&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027434089&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0027434089
VL - 7
SP - 210
EP - 214
JO - American Journal of Noninvasive Cardiology
JF - American Journal of Noninvasive Cardiology
SN - 0258-4425
IS - 4
ER -