Heart rate variability at different stages of congestive heart failure

S. Scalvini, M. Volterrani, E. Zanelli, C. Scotti, M. Pagani, A. Giordano

Research output: Contribution to journalArticle

Abstract

Purpose: Autonomic control of the cardiovascular system is deranged in chronic heart failure (CHF) and contributes to the pathophysiology of the syndrome. The present study was designed to evaluated whether clinical changes in the severity of heart failure coincide with different behaviour of autonomic nervous system. Methods: Thirty patients (pts) (mean age 62±8) with CHF, due to left ventricular systolic dysfunction, were divided into two group according to the severity of heart failure defined as NYHA functional class : Group 1 (15 pts with NYHA II) and Group 2 (15 pts with NYHA III-IV). Therapy was stable for almost three months and was not different between the two groups of pts. All the pts underwent 2D-echo Doppler (mean EF 28 ± 8% in the two groups) and 24-Holter monitoring. HRV was evaluated through the autoregressive spectral analysis with 600 neat ECG samples, while the subjects were 1-quietly recumbent (BS1), 2-with controlled breathing (15 acts/min) (RSC), 3-passive orthostatism after tilting (80%) (TLT). HRV was measured in both the time and frequency domain. Results: G1 pts showed an increase in high frequency component (HF) in baseline condition (p

Original languageEnglish
JournalChest
Volume110
Issue number4 SUPPL.
Publication statusPublished - Oct 1996

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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