TY - JOUR
T1 - Heart rate variability during specific sleep stages
T2 - A comparison of healthy subjects with patients after myocardial infarction
AU - Vanoli, E.
AU - Adamson, P. B.
AU - Ba-Lin, [No Value]
AU - Pinna, G. D.
AU - Lazzara, R.
AU - Orr, W. C.
PY - 1995
Y1 - 1995
N2 - Background: Heart rate variability (HRV) is typically higher during nighttime. This evidence supports the concept that overall, sleep is a condition during which vagal activity is dominant. Myocardial infarction (MI) results in a loss in the overall nocturnal HRV increase. However, the characteristics of HRV during specific sleep stages in normal subjects and, more importantly, after MI, are unknown. This study describes HRV during sleep stages in normal subjects and in patients with a recent MI. Methods and Results: HRV was measured from 5 minutes of continuous ECG recording in 8 subjects with no clinical evidence of coronary artery disease (age, 47±4 years) and in 8 patients with a recent MI (age, 51±2 years; NS versus control subjects) in the awake state, non-rapid eye movement (REM), and REM sleep. In normal subjects, the low- to high-frequency ratio (LF/HF) derived from power spectral analysis of HRV decreased significantly from the awake state to non-REM sleep (from 4±1.4 to 1.22±0.33, P
AB - Background: Heart rate variability (HRV) is typically higher during nighttime. This evidence supports the concept that overall, sleep is a condition during which vagal activity is dominant. Myocardial infarction (MI) results in a loss in the overall nocturnal HRV increase. However, the characteristics of HRV during specific sleep stages in normal subjects and, more importantly, after MI, are unknown. This study describes HRV during sleep stages in normal subjects and in patients with a recent MI. Methods and Results: HRV was measured from 5 minutes of continuous ECG recording in 8 subjects with no clinical evidence of coronary artery disease (age, 47±4 years) and in 8 patients with a recent MI (age, 51±2 years; NS versus control subjects) in the awake state, non-rapid eye movement (REM), and REM sleep. In normal subjects, the low- to high-frequency ratio (LF/HF) derived from power spectral analysis of HRV decreased significantly from the awake state to non-REM sleep (from 4±1.4 to 1.22±0.33, P
KW - heart rate
KW - myocardial infarction
KW - vagus nerve
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M3 - Article
C2 - 7895347
AN - SCOPUS:0028937701
VL - 91
SP - 1918
EP - 1922
JO - Circulation
JF - Circulation
SN - 0009-7322
IS - 7
ER -