Heat/burning sensation induced by topical application of capsaicin on perineal cutaneous area: New approach in diagnosis and treatment of chronic prostatitis/chronic pelvic pain syndrome?

Damiano Turini, Patrizia Beneforti, Michele Spinelli, Silvia Malagutti, Massimo Lazzeri

Research output: Contribution to journalArticle

Abstract

Objectives: To investigate the feasibility, safety, and efficacy of perineal cutaneous application of capsaicin as a test for the diagnosis, as well as a potential therapeutic tool, in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods: We recruited 22 patients (mean age 34.5 years, range 19 to 56), who had been diagnosed with CP/CPPS according to the National Institutes of Health criteria, and 6 healthy control subjects. Both groups received a topical application of 5 mL capsaicin at a concentration of 10-5 M to the perineal body skin. The patients were asked to mark on a visual analogue scale the intensity of any heat or burning sensation. All the patients had completed a National Institutes of Health Chronic Prostatitis Symptom Index before and 1 week after the test. The scores of the two groups were compared using the Mann-Whitney U test. Results: The patients with CP/CPPS reported a heat/burning sensation intensity that was statistically greater than that of the healthy controls (7.5 versus 4.3, P

Original languageEnglish
Pages (from-to)910-913
Number of pages4
JournalUrology
Volume67
Issue number5
DOIs
Publication statusPublished - May 2006

ASJC Scopus subject areas

  • Urology

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