HEFFICON: HIV effectiveness Italian conference

Andrea Antinori, Massimo Andreoni, Carlo Federico Perno, Adriano Lazzarin, Adriana Ammassari, Paolo Bonfanti, Stefano Bonora, Marco Borderi, Maria Rosaria Capobianchi, Antonella Castagna, Massimo Clementi, Paola Cinque, Antonella D'Arminio Monforte, Giovanni Di Perri, Massimo Galli, Andrea Gori, Paolo Maggi, Claudio Mastroianni, Cristina Mussini, Emanuale NicastriMassimo Puoti, Stefano Rusconi, Maria Santoro, Giuseppe Tambussi

Research output: Contribution to journalArticle

Abstract

Since the first acquired immunodeficiency syndrome cases were reported in 1981, more than 1.5 million people have been diagnosed with Human Immunodeficiency Virus-1 in Europe, including more than 136,000 new HIV cases in 2013. Recent epidemiological data estimate an incidence of 5-10 newly diagnosed HIV infections per 100,000 population per year in Europe and an average prevalence of infection of 5.7 cases per 100,000 population. In the absence of an effective curative strategy for HIV, optimization of prevention policies and clinical management of HIV positive patients is fundamental to reduce the impact of the HIV pandemic on public health. Clinical trials represent an essential tool for translating research findings into routine clinical practice. Careful evaluation and planning of clinical trials are therefore mandatory in order to provide relevant information to clinicians. The HEFFICON Project was conceived to investigate and pinpoint methodological issues and critical points that need to be addressed in future clinical studies to increase the translation of experimental results to the real life environment.

Original languageEnglish
Pages (from-to)149-184
Number of pages36
JournalNew Microbiologica
Volume38
Issue number2
Publication statusPublished - Apr 1 2015

Keywords

  • AIDS
  • HAART
  • HIV
  • Integrase inhibitors

ASJC Scopus subject areas

  • Microbiology (medical)
  • Medicine(all)

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    Antinori, A., Andreoni, M., Perno, C. F., Lazzarin, A., Ammassari, A., Bonfanti, P., Bonora, S., Borderi, M., Capobianchi, M. R., Castagna, A., Clementi, M., Cinque, P., D'Arminio Monforte, A., Di Perri, G., Galli, M., Gori, A., Maggi, P., Mastroianni, C., Mussini, C., ... Tambussi, G. (2015). HEFFICON: HIV effectiveness Italian conference. New Microbiologica, 38(2), 149-184.