Helicobacter pylori e patologia gastro-duodenale.

Translated title of the contribution: Helicobacter pylori and gastro-duodenal pathology

L. Villani, R. Fiocca, M. Perego, C. De Giacomo, E. Trespi, C. Alvisi, R. Turpini, E. Solcia

Research output: Contribution to journalArticle

Abstract

Helicobacter Pylori (HP) were found in 878 (73%) of 1205 patients undergoing upper G-I endoscopy with multiple biopsies for gastroduodenal diseases. HP were present in similar percentages among patients with active (89%) or healed (81%) peptic ulcer as well as in non ulcerous dyspeptics affected with gastritis (85%). 96% of active chronic gastritis were infected by HP as compared with 55% of quiescent gastritis. Antral gastritis was more frequently active in patients with ulcer diseases (76%) than in dyspeptic and asyntomatic patients (50%). Healed gastric and duodenal ulcers showed decreased incidence of active antral gastritis (69) as compared with active ulcers. Conversely body gastritis was more frequently active in healed (37%) than in overt (18%) duodenal ulcers. 95 histologically normal stomachs as well as 9 cases exhibiting type A gastritis were devoid of HP. High rates of infection were found in 610 cases of chronic gastritis without atrophy as well as in 151 atrophic antral (type B) gastritis. Cytoplasmic vacuolization and swelling of foveolar-superficial cells with adhering bacteria, micropapillae and microerosions were commonly found in HP-infected mucosa. In 16 of 19 children with type B chronic gastritis antibacterial therapy eradicated HP. This was followed by resolution or striking improvement of gastritis and disappearance of epithelial lesions.

Original languageItalian
Pages (from-to)707-717
Number of pages11
JournalPathologica
Volume82
Issue number1082
Publication statusPublished - Nov 1990

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Gastritis
Helicobacter pylori
Pathology
Duodenal Ulcer
Ulcer
Stomach Ulcer
Peptic Ulcer
Endoscopy
Atrophy
Stomach
Mucous Membrane
Bacteria
Biopsy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Helicobacter pylori e patologia gastro-duodenale. / Villani, L.; Fiocca, R.; Perego, M.; De Giacomo, C.; Trespi, E.; Alvisi, C.; Turpini, R.; Solcia, E.

In: Pathologica, Vol. 82, No. 1082, 11.1990, p. 707-717.

Research output: Contribution to journalArticle

Villani, L, Fiocca, R, Perego, M, De Giacomo, C, Trespi, E, Alvisi, C, Turpini, R & Solcia, E 1990, 'Helicobacter pylori e patologia gastro-duodenale.', Pathologica, vol. 82, no. 1082, pp. 707-717.
Villani L, Fiocca R, Perego M, De Giacomo C, Trespi E, Alvisi C et al. Helicobacter pylori e patologia gastro-duodenale. Pathologica. 1990 Nov;82(1082):707-717.
Villani, L. ; Fiocca, R. ; Perego, M. ; De Giacomo, C. ; Trespi, E. ; Alvisi, C. ; Turpini, R. ; Solcia, E. / Helicobacter pylori e patologia gastro-duodenale. In: Pathologica. 1990 ; Vol. 82, No. 1082. pp. 707-717.
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