Helicobacter pylori as cause of gastrointestinal disease in children with hemato-oncologic diseases

Elio Castagnola, Michaela Calvillo, Anna Rita Gigliotti, Francesca Fioredda, Guia Hanau, Ilaria Caviglia, Edoardo Lanino, Carlo Dufour

Research output: Contribution to journalArticlepeer-review

Abstract

After documentation of a case of life threatening Helicobacter pylori (H. pylori) gastric ulcer in an adolescent girl on treatment for acute lymphoblastic leukaemia, we started to systematically look for gastro-intestinal symptoms due to H. pylori infection in our cancer patients at G. Gaslini Children's Hospital. During a period of 46 months, we observed 13 further cases of severe dyspepsia syndrome or gastro intestinal bleeding associated with presence of H. pylori faecal antigen. All patients recovered with appropriate therapy. H. pylori may represent a cause of severe gastrointestinal complications in children with cancer or following bone marrow transplant.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalPediatric Blood and Cancer
Volume47
Issue number1
DOIs
Publication statusPublished - Jul 2006

Keywords

  • BMT
  • Hematology/oncology
  • Infections in immunocompromised hosts
  • Support care

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Pediatrics, Perinatology, and Child Health

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