Helicobacter pylori in metabolic related diseases

Gianenrico Rizzatti, Maria V. Matteo, Gianluca Ianiro, Giovanni Cammarota, Francesco Franceschi, Antonio Gasbarrini

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Helicobacter pylori is one of the most common gastrointestinal infection affecting humans worldwide. Hp colonizes the stomach with preferential trophism for the antrum. Hp infection is associated with the development of a chronic gastritis and subsequently with several gastric diseases such as peptic disease, gastric carcinoma and MALT lymphoma. Moreover, Helicobacter pylori infection has also been reported in literature to be associated with many other extra-gastric conditions including sideropenic anemia, thrombocytopenia, neurological, liver and cardiovascular diseases. For some conditions the association is supported by solid literature data and also by the identification of the possible physiopathogenetic mechanism involved. In other cases, the link is only reported by association studies often with conflicting results. In this context, diabetes mellitus, cardiovascular disorders and liver steatosis have all been reported to be associated with Helicobacter pylori infection. Interestingly, these conditions share many characteristics and they often overlap as they represent the expression of the so called metabolic syndrome. Aim of the review was to summarize the available data regarding the association between Helicobacter Pylori infection and diabetes mellitus, cardiovascular disorders and liver steatosis.

Original languageEnglish
Pages (from-to)297-309
Number of pages13
JournalMinerva Gastroenterologica e Dietologica
Volume64
Issue number3
DOIs
Publication statusPublished - Sep 1 2018

Fingerprint

Metabolic Diseases
Helicobacter pylori
Helicobacter Infections
Fatty Liver
Stomach
Diabetes Mellitus
Stomach Diseases
Marginal Zone B-Cell Lymphoma
Gastritis
Infection
Thrombocytopenia
Liver Diseases
Anemia
Digestion
Cardiovascular Diseases
Carcinoma

Keywords

  • Cardiovascular diseases
  • Diabetes mellitus
  • Helicobacter pylori
  • Metabolic syndrome
  • Non-alcoholic fatty liver disease

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics
  • Gastroenterology

Cite this

Helicobacter pylori in metabolic related diseases. / Rizzatti, Gianenrico; Matteo, Maria V.; Ianiro, Gianluca; Cammarota, Giovanni; Franceschi, Francesco; Gasbarrini, Antonio.

In: Minerva Gastroenterologica e Dietologica, Vol. 64, No. 3, 01.09.2018, p. 297-309.

Research output: Contribution to journalReview article

Rizzatti, Gianenrico ; Matteo, Maria V. ; Ianiro, Gianluca ; Cammarota, Giovanni ; Franceschi, Francesco ; Gasbarrini, Antonio. / Helicobacter pylori in metabolic related diseases. In: Minerva Gastroenterologica e Dietologica. 2018 ; Vol. 64, No. 3. pp. 297-309.
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