Helicobacter pylori infection and growth delay in older children

Francesco Perri, Maria Pastore, Gioacchino Leandro, Rocco Clemente, Yvo Ghoos, Marc Peeters, Vito Annese, Michèle Quitadamo, Anna Latiano, Paul Rutgeerts, Angelo Andriulli

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

It is thought that Helicobacter pylori infection may influence growth rate in children. The aim of this study was to evaluate the prevalence of H pylori infection in healthy Italian children, and to look for differences in height between infected and non-infected subjects. Two hundred and sixteen children, aged 3 to 14 years, were tested for H pylori infection by 13C- urea breath test. Centile values for height were calculated. Composite indices for socioeconomic class and household crowding were also determined. Forty nine of 216 children (22.7%) were H pylori positive. The prevalence of infection increased with age. Eight of 49 H pylori positive children (16.3%) were below the 25th centile for height, compared with 13 of 167 H pylori negative children (7.8%). This difference became significant in children aged 8.5 to 14 years; in this group (n = 127), eight of 31 infected children (25.8%) were below the 25th centile for height, compared with eight of 96 noninfected children (8.30/0). A significant correlation was found between socioeconomic conditions, household crowding, and H pylori status. By using stepwise logistic regression, only the centile value for height was significantly related to H pylori status in older children. Thus H pylori infection was associated with growth delay in older children, poor socioeconomic conditions, and household overcrowding. This finding is consistent with the hypothesis that H pylori infection is one of the environmental factors capable of affecting growth.

Original languageEnglish
Pages (from-to)46-49
Number of pages4
JournalArchives of Disease in Childhood
Volume77
Issue number1
Publication statusPublished - 1997

Fingerprint

Helicobacter Infections
Helicobacter pylori
Pylorus
Growth
Infection
Crowding
Breath Tests
Urea
Logistic Models

Keywords

  • Growth
  • Height
  • Helicobacter pylori
  • Urea breath test

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Perri, F., Pastore, M., Leandro, G., Clemente, R., Ghoos, Y., Peeters, M., ... Andriulli, A. (1997). Helicobacter pylori infection and growth delay in older children. Archives of Disease in Childhood, 77(1), 46-49.

Helicobacter pylori infection and growth delay in older children. / Perri, Francesco; Pastore, Maria; Leandro, Gioacchino; Clemente, Rocco; Ghoos, Yvo; Peeters, Marc; Annese, Vito; Quitadamo, Michèle; Latiano, Anna; Rutgeerts, Paul; Andriulli, Angelo.

In: Archives of Disease in Childhood, Vol. 77, No. 1, 1997, p. 46-49.

Research output: Contribution to journalArticle

Perri, F, Pastore, M, Leandro, G, Clemente, R, Ghoos, Y, Peeters, M, Annese, V, Quitadamo, M, Latiano, A, Rutgeerts, P & Andriulli, A 1997, 'Helicobacter pylori infection and growth delay in older children', Archives of Disease in Childhood, vol. 77, no. 1, pp. 46-49.
Perri F, Pastore M, Leandro G, Clemente R, Ghoos Y, Peeters M et al. Helicobacter pylori infection and growth delay in older children. Archives of Disease in Childhood. 1997;77(1):46-49.
Perri, Francesco ; Pastore, Maria ; Leandro, Gioacchino ; Clemente, Rocco ; Ghoos, Yvo ; Peeters, Marc ; Annese, Vito ; Quitadamo, Michèle ; Latiano, Anna ; Rutgeerts, Paul ; Andriulli, Angelo. / Helicobacter pylori infection and growth delay in older children. In: Archives of Disease in Childhood. 1997 ; Vol. 77, No. 1. pp. 46-49.
@article{96123441eeda4ad29a0c60a4bf2dd4a7,
title = "Helicobacter pylori infection and growth delay in older children",
abstract = "It is thought that Helicobacter pylori infection may influence growth rate in children. The aim of this study was to evaluate the prevalence of H pylori infection in healthy Italian children, and to look for differences in height between infected and non-infected subjects. Two hundred and sixteen children, aged 3 to 14 years, were tested for H pylori infection by 13C- urea breath test. Centile values for height were calculated. Composite indices for socioeconomic class and household crowding were also determined. Forty nine of 216 children (22.7{\%}) were H pylori positive. The prevalence of infection increased with age. Eight of 49 H pylori positive children (16.3{\%}) were below the 25th centile for height, compared with 13 of 167 H pylori negative children (7.8{\%}). This difference became significant in children aged 8.5 to 14 years; in this group (n = 127), eight of 31 infected children (25.8{\%}) were below the 25th centile for height, compared with eight of 96 noninfected children (8.30/0). A significant correlation was found between socioeconomic conditions, household crowding, and H pylori status. By using stepwise logistic regression, only the centile value for height was significantly related to H pylori status in older children. Thus H pylori infection was associated with growth delay in older children, poor socioeconomic conditions, and household overcrowding. This finding is consistent with the hypothesis that H pylori infection is one of the environmental factors capable of affecting growth.",
keywords = "Growth, Height, Helicobacter pylori, Urea breath test",
author = "Francesco Perri and Maria Pastore and Gioacchino Leandro and Rocco Clemente and Yvo Ghoos and Marc Peeters and Vito Annese and Mich{\`e}le Quitadamo and Anna Latiano and Paul Rutgeerts and Angelo Andriulli",
year = "1997",
language = "English",
volume = "77",
pages = "46--49",
journal = "Archives of Disease in Childhood",
issn = "0003-9888",
publisher = "BMJ Publishing Group",
number = "1",

}

TY - JOUR

T1 - Helicobacter pylori infection and growth delay in older children

AU - Perri, Francesco

AU - Pastore, Maria

AU - Leandro, Gioacchino

AU - Clemente, Rocco

AU - Ghoos, Yvo

AU - Peeters, Marc

AU - Annese, Vito

AU - Quitadamo, Michèle

AU - Latiano, Anna

AU - Rutgeerts, Paul

AU - Andriulli, Angelo

PY - 1997

Y1 - 1997

N2 - It is thought that Helicobacter pylori infection may influence growth rate in children. The aim of this study was to evaluate the prevalence of H pylori infection in healthy Italian children, and to look for differences in height between infected and non-infected subjects. Two hundred and sixteen children, aged 3 to 14 years, were tested for H pylori infection by 13C- urea breath test. Centile values for height were calculated. Composite indices for socioeconomic class and household crowding were also determined. Forty nine of 216 children (22.7%) were H pylori positive. The prevalence of infection increased with age. Eight of 49 H pylori positive children (16.3%) were below the 25th centile for height, compared with 13 of 167 H pylori negative children (7.8%). This difference became significant in children aged 8.5 to 14 years; in this group (n = 127), eight of 31 infected children (25.8%) were below the 25th centile for height, compared with eight of 96 noninfected children (8.30/0). A significant correlation was found between socioeconomic conditions, household crowding, and H pylori status. By using stepwise logistic regression, only the centile value for height was significantly related to H pylori status in older children. Thus H pylori infection was associated with growth delay in older children, poor socioeconomic conditions, and household overcrowding. This finding is consistent with the hypothesis that H pylori infection is one of the environmental factors capable of affecting growth.

AB - It is thought that Helicobacter pylori infection may influence growth rate in children. The aim of this study was to evaluate the prevalence of H pylori infection in healthy Italian children, and to look for differences in height between infected and non-infected subjects. Two hundred and sixteen children, aged 3 to 14 years, were tested for H pylori infection by 13C- urea breath test. Centile values for height were calculated. Composite indices for socioeconomic class and household crowding were also determined. Forty nine of 216 children (22.7%) were H pylori positive. The prevalence of infection increased with age. Eight of 49 H pylori positive children (16.3%) were below the 25th centile for height, compared with 13 of 167 H pylori negative children (7.8%). This difference became significant in children aged 8.5 to 14 years; in this group (n = 127), eight of 31 infected children (25.8%) were below the 25th centile for height, compared with eight of 96 noninfected children (8.30/0). A significant correlation was found between socioeconomic conditions, household crowding, and H pylori status. By using stepwise logistic regression, only the centile value for height was significantly related to H pylori status in older children. Thus H pylori infection was associated with growth delay in older children, poor socioeconomic conditions, and household overcrowding. This finding is consistent with the hypothesis that H pylori infection is one of the environmental factors capable of affecting growth.

KW - Growth

KW - Height

KW - Helicobacter pylori

KW - Urea breath test

UR - http://www.scopus.com/inward/record.url?scp=8544245714&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8544245714&partnerID=8YFLogxK

M3 - Article

VL - 77

SP - 46

EP - 49

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

SN - 0003-9888

IS - 1

ER -