Helicobacter pylori stool antigen test: A method to confirm eradication in children

Paola Roggero, Arianna Bonfiglio, Sergio Luzzani, Alberto Valadè, Elena Cataliotti, Giovanna Corno, Maria Cristina Garlaschi, Emanuela Carissimi, Fabio Mosca, Vittorio Cornelli

Research output: Contribution to journalArticle

Abstract

We evaluated an antigen-based stool assay as an indicator of Helicobacter pylori (Hp) status during treatment aimed at eradicating Hp in 22 Hp-positive patients and 63 negative control patients. The sensitivity and specificity of the assay was 100% and 70%, respectively, when the manufacturer's cutoff was used. When we used the cutoff calculated from a receiver operating characteristic curve, the specificity of this test increased. Under these conditions, the test could be used in monitoring treatment and verifying eradication of Hp infection. Further studies must be carried out to standardize the cutoff in children.

Original languageEnglish
Pages (from-to)775-777
Number of pages3
JournalJournal of Pediatrics
Volume140
Issue number6
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Roggero, P., Bonfiglio, A., Luzzani, S., Valadè, A., Cataliotti, E., Corno, G., Garlaschi, M. C., Carissimi, E., Mosca, F., & Cornelli, V. (2002). Helicobacter pylori stool antigen test: A method to confirm eradication in children. Journal of Pediatrics, 140(6), 775-777. https://doi.org/10.1067/mpd.2002.123662