Hemangiopericytoma of the nose: A case for both internal and external localization

Mauro Melato, Nader Gorji, Nives Jonjic

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Nasal and paranasal cavities are sites of predilection for hemangiopericytoma (HPC), a rare vascular tumor described for the first time in 1942. Because of their characteristics, i.e. clinical presentation, age distribution and biological behaviour, nasal HPCs are frequently reported as 'hemangioperycitoma-like intranasal tumors' although such a distinction from other HPCs is debated. Patients, methods and results: out of nearly 64,000 autopsies and 336,000 surgical and endoscopic biopsies performed at the University of Trieste over 30 years, only three cases of HPC have been found, two of them affecting the external nose; for both there was a good agreement between histology - supported by immunohistochemistry and flow cytometry - and biological behaviour. Conclusions. On the basis of the sparse literature on skin HPC and of our two cases, we suggest that not only the internal, but also the external nose should be considered a predilection site for HPC.

Original languageEnglish
Pages (from-to)717-721
Number of pages5
JournalAnticancer Research
Volume19
Issue number1 B
Publication statusPublished - 1999

Keywords

  • Haemangiopericytoma
  • Hemangiopericytoma
  • Nose
  • Vascular tumors

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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